Evidence map›Paper›PMID 35631864›Full record

ArticlePolymers2022

PVA-Based Electrospun Biomembranes with Hydrolyzed Collagen and Ethanolic Extract of

Alitzel Belém García-Hernández, Eduardo Morales-Sánchez, Blanca M Berdeja-Martínez, Monserrat Escamilla-García, Ma Paz Salgado-Cruz, Minerva Rentería-Ortega, Reynold R Farrera-Rebollo, Miguel A Vega-Cuellar, Georgina Calderón-Domínguez

Abstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alitzel Belém García-HernándezEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, CDMX, Mexico City 07738, Mexico.
Eduardo Morales-SánchezCentro de Investigación en Ciencia Aplicada y Tecnología Avanzada, Unidad Querétaro, Instituto Politécnico Nacional, Qro., Santiago de Querétaro 76090, Mexico.
Blanca M Berdeja-MartínezEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, CDMX, Mexico City 07738, Mexico.
Monserrat Escamilla-GarcíaDepartamento de Investigación en Alimentos y Estudios de Postgrado, Universidad Autónoma de Querétaro, Qro., Santiago de Querétaro 76010, Mexico.
Ma Paz Salgado-CruzEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, CDMX, Mexico City 07738, Mexico.
Minerva Rentería-OrtegaTecnológico Nacional de México/TES de San Felipe del Progreso, Edo. Méx., San Felipe del Progreso 50640, Mexico.
Reynold R Farrera-RebolloEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, CDMX, Mexico City 07738, Mexico.
Miguel A Vega-CuellarEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, CDMX, Mexico City 07738, Mexico.
Georgina Calderón-DomínguezEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, CDMX, Mexico City 07738, Mexico.ORCID 0000-0001-6468-5289

Funding

Consejo Nacional de Ciencia y Tecnología 1668Instituto Politécnico Nacional 20195500, 20201679, 20211381 and 20201695
6 · The paper itself

Abstract

Biological, physicochemical, structural, and thermal properties of PVA-based electrospun wound dressings added with hydrolyzed collagen (HC) and different concentrations of Hypericum perforatum ethanolic extract (EEHP) were studied. Membrane characterization was carried out by X-ray diffraction, Fourier infrared spectroscopy, differential scanning calorimetry, barrier properties, scanning electron microscopy, image analysis (diameter and pore size), as well as antimicrobial and anti-inflammatory activities. Results showed that the PVA/HC/EEHP materials, fabricated under controlled conditions of temperature and humidity, generated fiber membranes with diameters between 140−390 nm, adequate porosity and pore size for cell growth (67−90% and 4−16 µm, respectively), and good barrier properties (0.005−0.032 g·m−2 s−1) to be used in the treatment of conditions on the skin, and was even better than some commercial products. Finally, they showed to have anti-inflammatory (>80%), and antimicrobial activity against S. aureus and S. epiderm. Furthermore, higher crystalline structure was observed according to the EEHP concentration. In addition, this is the first report in which PVA/HC/EEHP membranes are successfully fabricated and characterized.

Indexed as

electrospinninghydrolyzed collagenHypericum perforatumpolyvinyl alcoholwound dressing

Identifiers

PMID35631864
PMCPMC9147280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.