Evidence map›Paper›PMID 35631586›Full record

ArticlePharmaceutics2022

D-Alpha-Tocopheryl Poly(ethylene Glycol 1000) Succinate-Coated Manganese-Zinc Ferrite Nanomaterials for a Dual-Mode Magnetic Resonance Imaging Contrast Agent and Hyperthermia Treatments.

Lin Wang, Syu-Ming Lai, Cun-Zhao Li, Hsiu-Ping Yu, Parthiban Venkatesan, Ping-Shan Lai

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Cancer diagnosis and treatment platform based on manganese-based nanomaterials.Frontiers in bioengineering and biotechnology · 2024
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lin WangCollege of Chemistry & Pharmacy, Northwest A&F University, Xianyang 712100, China.
Syu-Ming LaiDepartment of Chemistry, National Chung Hsing University, Taichung 402204, Taiwan.
Cun-Zhao LiDepartment of Chemistry, National Chung Hsing University, Taichung 402204, Taiwan.
Hsiu-Ping YuCollege of Chemistry & Pharmacy, Northwest A&F University, Xianyang 712100, China.
Parthiban VenkatesanDepartment of Chemistry, National Chung Hsing University, Taichung 402204, Taiwan.ORCID 0000-0003-0899-2625
Ping-Shan LaiDepartment of Chemistry, National Chung Hsing University, Taichung 402204, Taiwan.
National Chung Hsing University · TWNorthwest Institute of Mechanical and Electrical Engineering · CN

Funding

Ministry of Science and Technology of the Republic of China 106-2113-M-005-014-MY3;110-2124-M-005-001-MY3National Health Research Institutes NHRI-EX104-10114EC
6 · The paper itself

Abstract

Manganese-zinc ferrite (MZF) is known as high-performance magnetic material and has been used in many fields and development. In the biomedical applications, the biocompatible MZF formulation attracted much attention. In this study, water-soluble amphiphilic vitamin E (TPGS, d-alpha-tocopheryl poly(ethylene glycol 1000) succinate) formulated MZF nanoparticles were synthesized to serve as both a magnetic resonance imaging (MRI) contrast agent and a vehicle for creating magnetically induced hyperthermia against cancer. The MZF nanoparticles were synthesized from a metallic acetylacetonate in an organic phase and further modified with TPGS using an emulsion and solvent-evaporation method. The resulting TPGS-modified MZF nanoparticles exhibited a dual-contrast ability, with a longitudinal relaxivity (35.22 s

Indexed as

hyperthermiain vivomagnetic resonance imagingmanganese-zinc ferritetheranostic

Identifiers

PMID35631586
PMCPMC9144495
OpenAlexW4229369750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.