Evidence map›Paper›PMID 35631550›Full record

ArticlePharmaceutics2022

The Antitumoral/Antimetastatic Action of the Flavonoid Brachydin A in Metastatic Prostate Tumor Spheroids In Vitro Is Mediated by (Parthanatos) PARP-Related Cell Death.

Diego Luis Ribeiro, Katiuska Tuttis, Larissa Cristina Bastos de Oliveira, Juliana Mara Serpeloni, Izabela Natalia Faria Gomes, André van Helvoort Lengert, Cláudia Quintino da Rocha, Rui Manuel Reis, Ilce Mara de Syllos Cólus, Lusânia Maria Greggi Antunes

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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  4. Therapeutic Potential ofACS omega · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Diego Luis RibeiroDepartament of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, Brazil.ORCID 0000-0003-1715-966X
Katiuska TuttisDepartament of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto 14049-900, Brazil.ORCID 0000-0002-5624-8019
Larissa Cristina Bastos de OliveiraDepartment of General Biology, Center for Biological Sciences, State University of Londrina, Londrina 86057-970, Brazil.
Juliana Mara SerpeloniDepartment of General Biology, Center for Biological Sciences, State University of Londrina, Londrina 86057-970, Brazil.
Izabela Natalia Faria GomesMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, Brazil.ORCID 0000-0003-0551-138X
André van Helvoort LengertMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, Brazil.ORCID 0000-0002-3632-343X
Cláudia Quintino da RochaDepartment of Chemistry, Center for Exact Sciences and Technology, Federal University of Maranhão, São Luís 65080-805, Brazil.ORCID 0000-0002-3578-1869
Rui Manuel ReisMolecular Oncology Research Center, Barretos Cancer Hospital, Barretos 14784-400, Brazil.ORCID 0000-0002-9639-7940
Ilce Mara de Syllos CólusDepartment of General Biology, Center for Biological Sciences, State University of Londrina, Londrina 86057-970, Brazil.ORCID 0000-0001-9098-1698
Lusânia Maria Greggi AntunesDepartment of Clinical Analysis, Toxicology, and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, Brazil.ORCID 0000-0002-3079-4388
Hospital de Câncer de Barretos · BRUniversidade de São Paulo · BRUniversidade Estadual de Londrina · BRUniversidade Federal do Maranhão · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior National Postdoctoral Program PNPD grant # 88887.354023/2019 and Finance Code 001Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão grant # 00849/18National Council for Scientific and Technological Development Postdoctoral Fellowship grant #151520/2018-6 and Universal Project grant # 426246/2018-7São Paulo Research Foundation # 2017/22305-9
6 · The paper itself

Abstract

Metastatic prostate cancer (mPCa) is resistant to several chemotherapeutic agents. Brachydin A (BrA), a glycosylated flavonoid extracted from

Indexed as

cell deathchemotherapyFridericia platyphyllaprostate cancertumor spheroids

Identifiers

PMID35631550
PMCPMC9147598
OpenAlexW4225286210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.