Evidence map›Paper›PMID 35631509›Full record

ArticlePharmaceutics2022

Prismatic Silver Nanoparticles Decorated on Graphene Oxide Sheets for Superior Antibacterial Activity.

Thi Tuong Vi Truong, Chien-Chang Chen, Selvaraj Rajesh Kumar, Chih-Chien Hu, Dave W Chen, Yu-Kuo Liu, Shingjiang Jessie Lue

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Thi Tuong Vi TruongDivision of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Chien-Chang ChenDivision of Pediatric Gastroenterology and Hepatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-2881-3973
Selvaraj Rajesh KumarDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0003-0822-7843
Chih-Chien HuDepartment of Orthopedics, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Dave W ChenDepartment of Orthopedic Surgery, Chang Gung Memorial Hospital, Keelung City 204, Taiwan.
Yu-Kuo LiuDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan 333, Taiwan.
Shingjiang Jessie LueDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0003-1950-8093
Chang Gung University · TWChang Gung Memorial Hospital · TWMing Chi University of Technology · TW

Funding

Linkou Chang Gung Memorial Hospital CMRP2K0141
6 · The paper itself

Abstract

Spherical silver nanoparticles (Ag NPs) and silver nanoprisms (Ag NPrsms) were synthesized and decorated on graphene oxide (GO) nanosheets. The Ag contents were 29% and 23% in the GO−Ag NPs and GO−Ag NPrsms, respectively. The Ag NPrsms exhibited stronger (111) crystal signal than Ag NPs. The GO−Ag NPrsms exhibited higher Ag (I) content (75.6%) than GO-Ag NPs (69.9%). Increasing the nanomaterial concentration from 25 to 100 µg mL−1 improved the bactericidal efficiency, and the antibacterial potency was in the order: GO−Ag NPrsms > GO−Ag NPs > Ag NPrsms > Ag NPs > GO. Gram-positive Staphylococcus aureus (S. aureus) was more vulnerable than Gram-negative Escherichia coli (E. coli) upon exposure to these nanomaterials. The GO−Ag NPrsms demonstrated a complete (100%) bactericidal effect against S. aureus at a concentration of 100 µg mL−1. The GO−Ag composites outperformed those of Ag or GO due to the synergistic effect of bacteriostatic Ag particles and GO affinity toward bacteria. The levels of reactive oxygen species produced in the bacteria−nanomaterial mixtures were highly correlated to the antibacterial efficacy values. The GO−Ag NPrsms are promising as bactericidal agents to suppress biofilm formation and inhibit bacterial infection.

Indexed as

antibacterial activitygraphene oxidenanoparticlesnanoprismssilver nanoparticles

Identifiers

PMID35631509
PMCPMC9147939
OpenAlexW4224313344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.