Evidence map›Paper›PMID 35631474›Full record

ArticlePharmaceutics2022

Optimization of the Synthesis of Natural Polymeric Nanoparticles of Inulin Loaded with Quercetin: Characterization and Cytotoxicity Effect.

Jocelyn C Ayala-Fuentes, Melissa Zulahi Gallegos-Granados, Luis Jesús Villarreal-Gómez, Marilena Antunes-Ricardo, Daniel Grande, Rocio Alejandra Chavez-Santoscoy

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jocelyn C Ayala-FuentesTecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Ave. Eugenio Garza Sada 2501 Sur, Monterrey 64849, Mexico.ORCID 0000-0002-5652-6015
Melissa Zulahi Gallegos-GranadosFacultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Tijuana 22260, Mexico.
Luis Jesús Villarreal-GómezFacultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Tijuana 22260, Mexico.ORCID 0000-0002-4666-1408
Marilena Antunes-RicardoTecnologico de Monterrey, The Institute for Obesity Research, Ave. Eugenio Garza Sada 2501 Sur, Monterrey 64849, Mexico.ORCID 0000-0002-8546-6832
Daniel GrandeUniv Est Creteil, CNRS, Institut de Chimie et des Matériaux Paris-Est (ICMPE), 2, rue Henri Du-nant, 94320 Thiais, France.ORCID 0000-0002-9987-9961
Rocio Alejandra Chavez-SantoscoyTecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Ave. Eugenio Garza Sada 2501 Sur, Monterrey 64849, Mexico.ORCID 0000-0002-4551-1862
Tecnológico de Monterrey · MXUniversidad Autónoma de Baja California · MXCentre National de la Recherche Scientifique · FR

Funding

Monterrey Institute of Technology and Higher Education APC
6 · The paper itself

Abstract

Quercetin is a bioactive component that is capable of having therapeutic potential in the prevention of different noncommunicable chronic diseases (NCDs). However, it presents instability in the gastrointestinal tract in addition to low bioavailability. One way to overcome the limitations of quercetin lies in using nanotechnology for the development of nanoparticles, based on biopolymers, that are capable of being ingestible. Inulin, a fructan-type polysaccharide, acts as a delivery system for the release of quercetin in a target cell, guaranteeing the stability of the molecule. Inulin-coated quercetin nanoparticles were synthesized by the spray dryer method, and four variables were evaluated, namely inulin concentration (5-10%

Indexed as

flavonoidinulinnanoparticlequercetin

Identifiers

PMID35631474
PMCPMC9147723
OpenAlexW4224300720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.