Evidence map›Paper›PMID 35631412›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Promising Antibacterial and Antifungal Agents Based on Thiolated Vitamin K3 Analogs: Synthesis, Bioevaluation, Molecular Docking.

Hatice Yıldırım, Mahmut Yıldız, Nilüfer Bayrak, Emel Mataracı-Kara, Mohamed Osman Radwan, Ayse Tarbin Jannuzzi, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Hatice YıldırımDepartment of Chemistry, Faculty of Engineering, Istanbul University-Cerrahpasa, Avcilar, Istanbul 34320, Turkey.ORCID 0000-0003-3988-6120
Mahmut YıldızDepartment of Chemistry, Gebze Technical University, Gebze, Kocaeli 41400, Turkey.
Nilüfer BayrakDepartment of Chemistry, Faculty of Engineering, Istanbul University-Cerrahpasa, Avcilar, Istanbul 34320, Turkey.
Emel Mataracı-KaraDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Istanbul University, Beyazit, Istanbul 34116, Turkey.ORCID 0000-0002-4428-5066
Mohamed Osman RadwanMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.ORCID 0000-0002-9220-2659
Ayse Tarbin JannuzziDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Istanbul University, Beyazit, Istanbul 34116, Turkey.
Masami OtsukaMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.
Mikako FujitaMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.ORCID 0000-0001-6705-4052
Amaç Fatih TuYuNDepartment of Chemistry, Faculty of Science, Istanbul University, Fatih, Istanbul 34126, Turkey.ORCID 0000-0001-5698-1109
Istanbul University · TRIstanbul University-Cerrahpaşa · TRKumamoto University · JPFatih University · TRGebze Technical University · TRNational Research Centre · EG

Funding

the Scientific Research Projects Coordination Unit of Istanbul University FBA-2021-37260
6 · The paper itself

Abstract

In the present study, we designed and synthesized thiolated

Indexed as

antibacterial activityantibiofilm activityStaphylococcus aureusthymidylate kinaseVitamin K

Identifiers

PMID35631412
PMCPMC9146127
OpenAlexW4229442972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.