Evidence map›Paper›PMID 35631411›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Design, Semisynthesis, and Estrogenic Activity of Lignan Derivatives from Natural Dibenzylbutyrolactones.

Priscila López-Rojas, Ángel Amesty, Miguel Guerra-Rodríguez, Yeray Brito-Casillas, Borja Guerra, Leandro Fernández-Pérez, Ana Estévez-Braun

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Cognitive-enhancing effect ofRSC advances · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Priscila López-RojasDepartamento de Química Orgánica, Instituto Universitario de Bio-Orgánica, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez 2, 38206 La Laguna, Tenerife, Spain.
Ángel AmestyDepartamento de Química Orgánica, Instituto Universitario de Bio-Orgánica, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez 2, 38206 La Laguna, Tenerife, Spain.
Miguel Guerra-RodríguezInstituto Universitario de Investigaciones Biomédicas y Sanitarias (IUIBS), Universidad de Las Palmas de Gran Canaria (ULPGC), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-0047-1131
Yeray Brito-CasillasInstituto Universitario de Investigaciones Biomédicas y Sanitarias (IUIBS), Universidad de Las Palmas de Gran Canaria (ULPGC), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas de Gran Canaria, Spain.
Borja GuerraInstituto Universitario de Investigaciones Biomédicas y Sanitarias (IUIBS), Universidad de Las Palmas de Gran Canaria (ULPGC), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0003-4355-5682
Leandro Fernández-PérezInstituto Universitario de Investigaciones Biomédicas y Sanitarias (IUIBS), Universidad de Las Palmas de Gran Canaria (ULPGC), Paseo Blas Cabrera Felipe s/n, 35016 Las Palmas de Gran Canaria, Spain.ORCID 0000-0001-7802-465X
Ana Estévez-BraunDepartamento de Química Orgánica, Instituto Universitario de Bio-Orgánica, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez 2, 38206 La Laguna, Tenerife, Spain.

Funding

Agencia Canaria de Investigación, Innovación y Sociedad de la Información ProID2017010071Agencia Canaria de Investigación, Innovación y Sociedad de la Información ProID2021010037Ministerio de Ciencia, Innovación y Universidades RTI2018-094356-B-C21
6 · The paper itself

Abstract

Based on molecular docking studies on the ERα, a series of lignan derivatives (

Indexed as

estrogenic and antiestrogenic activitiesinduced fit docking (IFD)lignansmolecular dynamics (MD)natural products

Identifiers

PMID35631411
PMCPMC9145393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.