Evidence map›Paper›PMID 35631410›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Virtual Screening Based on Machine Learning Explores Mangrove Natural Products as KRAS

Lianxiang Luo, Tongyu Zheng, Qu Wang, Yingling Liao, Xiaoqi Zheng, Ai Zhong, Zunnan Huang, Hui Luo

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lianxiang LuoThe Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang 524023, China.ORCID 0000-0002-3391-9713
Tongyu ZhengThe First Clinical College, Guangdong Medical University, Zhanjiang 524023, China.
Qu WangThe First Clinical College, Guangdong Medical University, Zhanjiang 524023, China.
Yingling LiaoThe First Clinical College, Guangdong Medical University, Zhanjiang 524023, China.
Xiaoqi ZhengThe First Clinical College, Guangdong Medical University, Zhanjiang 524023, China.
Ai ZhongThe First Clinical College, Guangdong Medical University, Zhanjiang 524023, China.
Zunnan HuangSchool of Pharmacy, Guangdong Medical University, Dongguan 523808, China.ORCID 0000-0002-5821-703X
Hui LuoThe Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang 524023, China.
Guangdong Medical College · CN

Funding

Basic and Applied Basic Research Program of Guangdong Province 2019A1515110201Discipline Construction Project of Guangdong Medical University 4SG21004GInnovation and Entrepreneurship Team Leads the Pilot Program of Zhanjiang 2020LHJH005Program of Department of Natural Resources of Guangdong Province [2021]53
6 · The paper itself

Abstract

Mangrove secondary metabolites have many unique biological activities. We identified lead compounds among them that might target KRAS

Indexed as

drug discoveryKRASG12Cmachine learningmangrove natural productsmolecular dockingmolecular dynamicsvirtual screening

Identifiers

PMID35631410
PMCPMC9146975
OpenAlexW4229374235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.