Evidence map›Paper›PMID 35631390›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Antifungal Thiazolidines: Synthesis and Biological Evaluation of Mycosidine Congeners.

Igor B Levshin, Alexander Y Simonov, Sergey N Lavrenov, Alexey A Panov, Natalia E Grammatikova, Alexander A Alexandrov, Eslam S M O Ghazy, Nikita A Savin, Peter V Gorelkin, Alexander S Erofeev and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Antitumor, biological and nonlinear optical activities of novel thiazolidines.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Igor B LevshinGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.
Alexander Y SimonovGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.
Sergey N LavrenovGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.
Alexey A PanovGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.
Natalia E GrammatikovaGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.
Alexander A AlexandrovBach Institute of Biochemistry, Federal Research Center of Biotechnology of the RAS, 119071 Moscow, Russia.ORCID 0000-0001-7250-4740
Eslam S M O GhazyBach Institute of Biochemistry, Federal Research Center of Biotechnology of the RAS, 119071 Moscow, Russia.
Nikita A SavinResearch Laboratory of Biophysics, National University of Science and Technology "MISiS", 4 Leninsky Ave., 119049 Moscow, Russia.
Peter V GorelkinResearch Laboratory of Biophysics, National University of Science and Technology "MISiS", 4 Leninsky Ave., 119049 Moscow, Russia.ORCID 0000-0002-4860-9013
Alexander S ErofeevResearch Laboratory of Biophysics, National University of Science and Technology "MISiS", 4 Leninsky Ave., 119049 Moscow, Russia.
Vladimir I PolshakovFaculty of Fundamental Medicine, Lomonosov Moscow State University, 27/1 Lomonosovsky Ave., 119991 Moscow, Russia.
Gause Institute of New Antibiotics Russian Academy of Medical Sciences · RUNational University of Science and Technology · RUA N Bach Institute of Biochemistry · RULomonosov Moscow State University · RUPeoples' Friendship University of Russia · RU

Funding

Russian Science Foundation (#21-74-10115Russian Science Foundation (#22-23-00160
6 · The paper itself

Abstract

Novel derivatives of Mycosidine (3,5-substituted thiazolidine-2,4-diones) are synthesized by Knoevenagel condensation and reactions of thiazolidines with chloroformates or halo-acetic acid esters. Furthermore, 5-Arylidene-2,4-thiazolidinediones and their 2-thioxo analogs containing halogen and hydroxy groups or di(benzyloxy) substituents in 5-benzylidene moiety are tested for antifungal activity in vitro. Some of the synthesized compounds exhibit high antifungal activity, both fungistatic and fungicidal, and lead to morphological changes in the

Indexed as

antifungal activitycell walldrug designglucose transportthiazolidine-2,4-dione

Identifiers

PMID35631390
PMCPMC9145892
OpenAlexW4225278482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.