Evidence map›Paper›PMID 35631360›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Cobalt Bis-Dicarbollide Enhances Antibiotics Action towards

Eva Vaňková, Kristýna Lokočová, Petra Kašparová, Romana Hadravová, Ivana Křížová, Olga Maťátková, Jan Masák, Václav Šícha

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Eva VaňkováDepartment of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.ORCID 0000-0001-8863-0696
Kristýna LokočováDepartment of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.
Petra KašparováDepartment of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.
Romana HadravováInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo náměstí 542/2, 166 10 Prague, Czech Republic.
Ivana KřížováDepartment of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.ORCID 0000-0002-0497-4924
Olga MaťátkováDepartment of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.ORCID 0000-0002-3646-9738
Jan MasákDepartment of Biotechnology, University of Chemistry and Technology Prague, Technická 5, 166 28 Prague, Czech Republic.ORCID 0000-0001-6484-0824
Václav ŠíchaChemistry Department, Faculty of Science, Jan Evangelista Purkyně University in Ústí nad Labem, Pasteurova 15, 400 96 Ústí nad Labem, Czech Republic.ORCID 0000-0003-3163-1764
University of Chemistry and Technology, Prague · CZCzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZJan Evangelista Purkyně University in Ústí nad Labem · CZ

Funding

European Regional Development Fund ERDF/ESF Project "UniQSurf - Centre of biointerfaces and hybrid functional materials" CZ.02.1.01/0.0/0.0/17_048/0007411European Regional Development Fund; OP RDE CZ.02.1.01/0.0/0.0/16_019/0000729RVO project 61388963
6 · The paper itself

Abstract

The emergence of antibiotic resistance in opportunistic pathogens represents a huge problem, the solution for which may be a treatment with a combination of multiple antimicrobial agents. Sodium salt of cobalt bis-dicarbollide (COSAN.Na) is one of the very stable, low-toxic, amphiphilic boron-rich sandwich complex heteroboranes. This compound has a wide range of potential applications in the biological sciences due to its antitumor, anti-HIV-1, antimicrobial and antibiofilm activity. Our study confirmed the ability of COSAN.Na (in the concentration range 0.2-2.48 µg/mL) to enhance tetracycline, erythromycin, and vancomycin action towards

Indexed as

additive effectantibioticsantimicrobial activitycarboraneerythromycinGram-positive bacteriummetallacarboranessynergistic effecttetracyclinevancomycin

Identifiers

PMID35631360
PMCPMC9147877
OpenAlexW4224920934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.