Evidence map›Paper›PMID 35631329›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Design and Synthesis of a Novel 4-aryl-N-(2-alkoxythieno [2,3-

Eun-Sil Lee, Nayeon Kim, Joon Hee Kang, Aizhan Abdildinova, Seon-Hyeong Lee, Myung Hwi Lee, Nam Sook Kang, Tae-Sung Koo, Soo-Youl Kim, Young-Dae Gong

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Eun-Sil LeeInnovative Drug-Like Library Research Center, Dongguk University, Pil-dong 3-ga, Jung-gu, Seoul 100-715, Korea.
Nayeon KimInnovative Drug-Like Library Research Center, Dongguk University, Pil-dong 3-ga, Jung-gu, Seoul 100-715, Korea.
Joon Hee KangDivision of Cancer Biology, National Cancer Center, Research Institute, Goyang 410-769, Korea.
Aizhan AbdildinovaInnovative Drug-Like Library Research Center, Dongguk University, Pil-dong 3-ga, Jung-gu, Seoul 100-715, Korea.ORCID 0000-0002-3577-0270
Seon-Hyeong LeeDivision of Cancer Biology, National Cancer Center, Research Institute, Goyang 410-769, Korea.ORCID 0000-0001-6492-1499
Myung Hwi LeeGraduate School of New Drug Discovery and Development, Chungnam National University, Daehak-ro 99, Yuseong-gu, Daejeon 305-764, Korea.
Nam Sook KangGraduate School of New Drug Discovery and Development, Chungnam National University, Daehak-ro 99, Yuseong-gu, Daejeon 305-764, Korea.
Tae-Sung KooGraduate School of New Drug Discovery and Development, Chungnam National University, Daehak-ro 99, Yuseong-gu, Daejeon 305-764, Korea.ORCID 0000-0001-8046-6836
Soo-Youl KimDivision of Cancer Biology, National Cancer Center, Research Institute, Goyang 410-769, Korea.
Young-Dae GongInnovative Drug-Like Library Research Center, Dongguk University, Pil-dong 3-ga, Jung-gu, Seoul 100-715, Korea.ORCID 0000-0002-7963-7789
Dongguk University · KRChungnam National University · KRNational Cancer Center · KR

Funding

National Research Foundation of Korea 2021R1F1A1058004
6 · The paper itself

Abstract

Cancer cells are characterized by an abnormal cell cycle. Therefore, the cell cycle has been a potential target for cancer therapeutic agents. We developed a new lead compound,

Indexed as

anticancer activityCDC4-cJUNcell cycle arrestcolorectal cancerG2/M arrestlead compound

Identifiers

PMID35631329
PMCPMC9143821
OpenAlexW4224253965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.