Evidence map›Paper›PMID 35631301›Full record

ReviewNutrients2022

Anthocyanins in Chronic Diseases: The Power of Purple.

Sunil K Panchal, Oliver D John, Michael L Mathai, Lindsay Brown

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Flavonoids: Hemorheological effects and mechanisms of action.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Anthocyanins From Sweet Potatoes (Food science & nutrition · 2025
    Review
  12. Review
  13. In Vitro Evaluation of the Protective Efficacy ofMolecules (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Sunil K PanchalSchool of Science, Western Sydney University, Penrith, NSW 2753, Australia.ORCID 0000-0001-5464-3376
Oliver D JohnFaculty of Science and Natural Resources, Universiti Malaysia Sabah, Kota Kinabalu 88400, Sabah, Malaysia.ORCID 0000-0001-5035-1878
Michael L MathaiInstitute of Health and Sport, College of Health and Biomedicine, Victoria University, Melbourne, VIC 3021, Australia.
Lindsay BrownSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD 4222, Australia.
Florey Institute of Neuroscience and Mental Health · AUGriffith University · AUUniversiti of Malaysia Sabah · MYWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthocyanins are mainly purple-coloured phenolic compounds of plant origin that as secondary metabolites are important in plant survival. Understanding their health benefits in humans requires sourcing these unstable compounds in sufficient quantities at a reasonable cost, which has led to improved methods of extraction. Dark-coloured fruits, cereals and vegetables are current sources of these compounds. The range of potential sustainable sources is much larger and includes non-commercialised native plants from around the world and agri-waste containing anthocyanins. In the last 5 years, there have been significant advances in developing the therapeutic potential of anthocyanins in chronic human diseases. Anthocyanins exert their beneficial effects through improvements in gut microbiota, oxidative stress and inflammation, and modulation of neuropeptides such as insulin-like growth factor-1. Their health benefits in humans include reduced cognitive decline; protection of organs such as the liver, as well as the cardiovascular system, gastrointestinal tract and kidneys; improvements in bone health and obesity; and regulation of glucose and lipid metabolism. This review summarises some of the sources of anthocyanins and their mechanisms and benefits in the treatment of chronic human diseases.

Indexed as

AnthocyaninsVegetablesChronic DiseaseEdible GrainFruitHumansAnthocyaninsagri-wasteanthocyaninsgut microbiotainflammationoxidative stresstropical fruit

Identifiers

PMID35631301
PMCPMC9142943
OpenAlexW4282914926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.