Evidence map›Paper›PMID 35631300›Full record

Trial reportNutrients2022

Minimal Effects of Medium-Chain Triglyceride Supplementation on the Intestinal Microbiome Composition of Premature Infants: A Single-Center Pilot Study.

Jesús A Romo, Amanda B Arsenault, Sonia S Laforce-Nesbitt, Joseph M Bliss, Carol A Kumamoto

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jesús A RomoDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, USA.ORCID 0000-0002-1683-2288
Amanda B ArsenaultDepartment of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, RI 02905, USA.
Sonia S Laforce-NesbittDepartment of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, RI 02905, USA.
Joseph M BlissDepartment of Pediatrics, Women & Infants Hospital of Rhode Island, Providence, RI 02905, USA.ORCID 0000-0002-7425-1895
Carol A KumamotoDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, USA.
Providence College · USTufts University · US

Funding

Tufts IRACDAK12GM133314 · NIGMS · TUFTS UNIVERSITY BOSTON · PI CLAIRE L MOORE, Jamie Lynn Maguire · 2019 to 2026
$8.4M
Infectious Disease Training-Pathogenesis/Host ResponseT32AI007329 · NIAID · TUFTS MEDICAL CENTER · PI HU, LINDEN T · 1988 to 2018
$4.1M
Dietary Supplementation of Medium Chain Triglyceride (MCT) Oil to Reduce Candida Colonization in Preterm InfantsR21HD089278 · NICHD · TUFTS UNIVERSITY BOSTON · PI BLISS, JOSEPH MARK, KUMAMOTO, CAROL A. · 2017 to 2018
$461k
NIAID NIH HHS T32 AI007329NICHD NIH HHS R21 HD089278NIGMS NIH HHS K12 GM133314NIH HHS K12GM133314NIH HHS R21 HD089278NIH HHS T32AI007329
6 · The paper itself

Abstract

Compared to term infants, the microbiota of preterm infants is less diverse and often enriched for potential pathogens (e.g., members of the family Enterobacteriaceae). Additionally, antibiotics are frequently given to preterm infants, further destabilizing the microbiota and increasing the risk of fungal infections. In a previous communication, our group showed that supplementation of the premature infant diet with medium-chain triglyceride (MCT) oil reduced the fungal burden of

Indexed as

Gastrointestinal MicrobiomeInfant, PrematureBacteriaDietary SupplementsHumansInfantInfant, NewbornPilot ProjectsTriglyceridesTriglyceridesEnterobacteriaceaemedium-chain triglyceridemicrobiomepremature infantssupplementation

Identifiers

PMID35631300
PMCPMC9145469
OpenAlexW4281294054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.