Evidence map›Paper›PMID 35631262›Full record

ArticleNutrients2022

Anticholinergic Load Is Associated with Swallowing Dysfunction in Convalescent Older Patients after a Stroke.

Eiji Kose, Toshiyuki Hirai, Toshiichi Seki, Michiyo Okudaira, Nobuhiro Yasuno

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Eiji KoseDepartment of Pharmacy, Teikyo University School of Medicine University Hospital, Tokyo 173-8606, Japan.ORCID 0000-0002-5094-2122
Toshiyuki HiraiDepartment of Pharmacy, Hitachinaka General Hospital, Ibaraki 312-0057, Japan.
Toshiichi SekiDepartment of Pharmacy, Hitachinaka General Hospital, Ibaraki 312-0057, Japan.
Michiyo OkudairaLaboratory of Hospital Pharmacy, School of Pharmacy, Teikyo University, Tokyo 173-8606, Japan.
Nobuhiro YasunoDepartment of Pharmacy, Teikyo University School of Medicine University Hospital, Tokyo 173-8606, Japan.
Teikyo University Hospital · JPHitachi General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to establish whether anticholinergic load affects the swallowing function of geriatric stroke patients in convalescent stages, as no proven association between the anticholinergic load-based Anticholinergic Risk Scale and the swallowing dysfunction in Japanese patients was known. A retrospective cohort study was conducted on hospitalized older patients undergoing rehabilitation after stroke. The study outcomes included evaluating the patients at hospital discharge using the Functional Oral Intake Scale. To evaluate the effects of an increased anticholinergic load, we used a multivariate analysis to examine whether the change in the Anticholinergic Risk Scale during hospitalization was associated with the outcome. Of 542 enrolled patients, 345 (63.7%) presented with cerebral infarction, 148 (27.3%) with intracerebral hemorrhage, and 49 (9%) with subarachnoid hemorrhage. The change in the Anticholinergic Risk Scale was independently associated with the Functional Oral Intake Scale (β = -0.118,

Indexed as

StrokeStroke RehabilitationAgedCholinergic AntagonistsDeglutitionHumansRetrospective StudiesCholinergic Antagonistsanticholinergic loadfunctional oral intake scalestroke rehabilitationswallowing dysfunction

Identifiers

PMID35631262
PMCPMC9143519
OpenAlexW4280564802

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.