SynthesisNutrients2022
The Effect of Exercise and Nutritional Interventions on Body Composition in Patients with Advanced or Metastatic Cancer: A Systematic Review.
Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exercise and pathologic complete response to cancer treatment: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Low muscle mass, obesity, and cause-specific mortality in cancer patients: a nationwide cohort study.Cancer causes & control : CCC · 2026Article
- The effectiveness of concurrent training in lung cancer survivors: a systematic review.Translational lung cancer research · 2026Review
- Physical Activity Is Associated with Higher Retinal Microvascular Density in Uveal Melanoma and Nevus.Cancers · 2026Article
- Nutrition rehabilitation programs and cachexia clinics for anorexia-cachexia syndrome in patients with cancer.The oncologist · 2026Review
- Overview of research and practice progress in body composition measurement techniques.Frontiers in medical technology · 2026Review
- Development and application of a risk prediction nomogram for sarcopenia one year after surgery in early-stage non-small cell lung cancer patients.Frontiers in medicine · 2026Article
- Review
- Design of debunking the frailty-sarcopenia-ADT axis in metastatic prostate cancer with multicomponent exercise: the FIERCE trial protocol.Frontiers in sports and active living · 2025Article
- Body composition in early breast cancer patients treated with adjuvant aromatase inhibitors: Does dietary counseling matter?Breast (Edinburgh, Scotland) · 2024Observational
- Integrative Oncology Approaches to Supporting Immune Checkpoint Inhibitor Treatment of Solid Tumours.Current oncology reports · 2024Review
- Impact of exercise on cancer: mechanistic perspectives and new insights.Frontiers in immunology · 2024Review
- Exercise and Nutrition Interventions for Prehabilitation in Hepato-Pancreato-Biliary Cancers: A Narrative Review.Nutrients · 2023Review
- Piloting HealthScore: Feasibility and acceptability of a clinically integrated health coaching program for people living with cancer.Cancer medicine · 2023Article
- Effect of combined therapies including nutrition and physical exercise in advanced cancer patients: A pooled analysis.Frontiers in nutrition · 2023Article
- The associations between lipid profiles and visceral obesity among gastrointestinal cancer patients: a cross-sectional study.Lipids in health and disease · 2022Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advanced and metastatic cancers significantly alter body composition, leading to decreased lean mass and variable effects on fat mass. These effects on body composition are associated with significant physical dysfunction and poor prognosis in patients with cancer. Whilst exercise and nutritional interventions are likely to be of benefit in counteracting these effects, relatively little is known about using such interventions in patients with advanced or metastatic cancer. Therefore, in this systematic review we examine the effect of exercise and combined exercise and nutritional interventions on lean mass and fat mass among patients diagnosed with advanced or metastatic cancer. Following PRISMA guidelines, we identified 20 articles from PubMed, EMBASE, CINAHL, Cochrane CENTRAL, PEDro, SPORTDiscus, and REHABDATA. Overall, advanced or metastatic cancer populations comprising of mixed cancer types were most commonly examined (
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Registered trials
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