Evidence map›Paper›PMID 35631230›Full record

ArticleNutrients2022

Identification of Lifestyle Risk Factors in Adolescence Influencing Cardiovascular Health in Young Adults: The BELINDA Study.

Jules Morcel, Laurent Béghin, Nathalie Michels, Jérémy Vanhelst, Julien Labreuche, Elodie Drumez, Angela Polito, Marika Ferrari, Laura Censi, Dominique Deplanque and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Jules MorcelINFINITE-Institute for Translational Research in Inflammation (U-1286), Université de Lille, CHU Lille, Inserm, 59000 Lille, France.ORCID 0000-0002-5573-8331
Laurent BéghinINFINITE-Institute for Translational Research in Inflammation (U-1286), Université de Lille, CHU Lille, Inserm, 59000 Lille, France.
Nathalie MichelsDepartment of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-3069-7254
Jérémy VanhelstINFINITE-Institute for Translational Research in Inflammation (U-1286), Université de Lille, CHU Lille, Inserm, 59000 Lille, France.ORCID 0000-0002-0570-1522
Julien LabreucheMETRICS-Évaluation des Technologies de Santé et des Pratiques Médicales et Département de Biostatistiques, Université de Lille, CHU Lille, 59000 Lille, France.
Elodie DrumezMETRICS-Évaluation des Technologies de Santé et des Pratiques Médicales et Département de Biostatistiques, Université de Lille, CHU Lille, 59000 Lille, France.
Angela PolitoCouncil for Agricultural Research and Economics-Research Center on Food and Nutrition, 00178 Rome, Italy.ORCID 0000-0003-4898-796X
Marika FerrariCouncil for Agricultural Research and Economics-Research Center on Food and Nutrition, 00178 Rome, Italy.
Laura CensiCouncil for Agricultural Research and Economics-Research Center on Food and Nutrition, 00178 Rome, Italy.ORCID 0000-0002-8769-6914
Dominique DeplanqueClinical Investigation Center, Université de Lille, CHU Lille, Inserm, 59000 Lille, France.
María Luisa Miguel-BergesGENUD (Growth, Exercise, Nutrition and Development) Research Group, Instituto de Investigación Agroalimentaria de Aragón (IA2), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-2411-9538
Thaïs De RuyterDepartment of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-0174-8673
Stefaan De HenauwDepartment of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium.
Luis A MorenoGENUD (Growth, Exercise, Nutrition and Development) Research Group, Instituto de Investigación Agroalimentaria de Aragón (IA2), Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-0454-653X
Frédéric GottrandINFINITE-Institute for Translational Research in Inflammation (U-1286), Université de Lille, CHU Lille, Inserm, 59000 Lille, France.ORCID 0000-0002-5290-0436
Inserm · FRCereal Research Centre · ITGhent University · BEUniversidad de Zaragoza · ESUniversité de Lille · FR

Funding

Alpro Foundation 2018 A18_TT_0350ASTRE REGION 2013_13081-13082-13083European Commission Sixth RTD Framework Program FOOD-CT-20056007034Fondation de l'Université de Lille FUDL_BELINDA_2020
6 · The paper itself

Abstract

Cardiovascular diseases are the leading cause of mortality worldwide. These diseases originate in childhood, and a better understanding of their early determinants and risk factors would allow better prevention. The BELINDA (BEtter LIfe by Nutrition During Adulthood) study is a 10−14-year follow-up of the HEalthy Lifestyle in Europe by Nutrition in Adolescence study (the HELENA study, a European cross-sectional study in adolescents). The study aims to evaluate cardiovascular risk using the PDAY (Pathobiological Determinants of Atherosclerosis in Youth) risk score during young adulthood (21−32 years), and to examine the impact of risk factors identified during adolescence (12.5−17.5 years). Our secondary objective is to compare the characteristics of the BELINDA study population with the HELENA population not participating in the follow-up study. The HELENA study recruited 3528 adolescents during 2006−2007 and reassessed 232 of them 10−14 years later as young adults. We assessed clinical status, anthropometry, nutrition, physical activity (including sedentary behavior), physical fitness, and mental health parameters, and collected biological samples (blood, stool, and hair). Dietary intake, and physical activity and fitness data were also collected. A multivariable linear regression model will be used for the analysis of the primary outcome. A Chi-square and T-test were conducted for the comparison of the descriptive data (gender, age, weight, height, body mass index (BMI), and maternal school level) between participating and non-participating BELINDA adolescents. When comparing the 1327 eligible subjects with the 232 included in the BELINDA study, no significant differences regarding gender (p = 0.72), age (p = 0.60), height (p = 0.11), and weight (p = 0.083) at adolescence were found. However, the participating population had a lower BMI (20.4 ± 3.1 kg/m2 versus 21.2 ± 3.6 kg/m2; p < 0.001) and a higher maternal educational level (46.8% high school or university level versus 38.6%; p = 0.027) than the HELENA population who did not participate in the BELINDA study. The complete phenotyping obtained at adolescence through the HELENA study is a unique opportunity to identify adolescent risk factors for cardiovascular diseases. This paper will serve as a methodological basis for future analysis of this study.

Indexed as

Cardiovascular DiseasesAdolescentAdultCross-Sectional StudiesFollow-Up StudiesHumansLife StyleRisk FactorsYoung AdultadolescenceBELINDA studycardiovascular risk factorslifestylenutritionyoung adults

Identifiers

PMID35631230
PMCPMC9146351
OpenAlexW4280566273

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.