Evidence map›Paper›PMID 35630751›Full record

ArticleMolecules (Basel, Switzerland)2022

New Potential Pharmacological Targets of Plant-Derived Hydroxyanthraquinones from

Petko Alov, Merilin Al Sharif, Hristo Najdenski, Tania Pencheva, Ivanka Tsakovska, Maya Margaritova Zaharieva, Ilza Pajeva

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Petko AlovInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-1320-2173
Merilin Al SharifInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-2182-2006
Hristo NajdenskiThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-3221-2545
Tania PenchevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-1439-8895
Ivanka TsakovskaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-1389-1685
Maya Margaritova ZaharievaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-8548-5649
Ilza PajevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-5412-1586
Bulgarian Academy of Sciences · BG

Funding

Ministry of Education and Science of Bulgaria National Research Program "Healthy Foods for a Strong Bio-Economy and Quality of Life" approved by DCM # 577 / 17.08.2018
6 · The paper itself

Abstract

The increased use of polyphenols nowadays poses the need for identification of their new pharmacological targets. Recently, structure similarity-based virtual screening of DrugBank outlined pseudopurpurin, a hydroxyanthraquinone from

Indexed as

DNA Topoisomerase IVRubiaAnti-Bacterial AgentsDNA GyraseGatifloxacinMolecular Docking SimulationPolyphenolsAnti-Bacterial AgentsDNA GyraseDNA Topoisomerase IVGatifloxacinPolyphenolsantibacterial actionDNA gyraseDNA topoisomerase IVdockingpseudopurpurinsimilarity-based screening

Identifiers

PMID35630751
PMCPMC9145346
OpenAlexW4280636579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.