Evidence map›Paper›PMID 35630629›Full record

ArticleMolecules (Basel, Switzerland)2022

Synergistic Interactions between Tocol and Phenolic Extracts from Different Tree Nut Species against Human Cancer Cell Lines.

Jazmín C Stevens-Barrón, Abraham Wall-Medrano, Emilio Álvarez-Parrilla, Imelda Olivas-Armendáriz, Humberto Astiazaran-García, Ramón E Robles-Zepeda, Laura A De la Rosa

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jazmín C Stevens-BarrónDepartment of Chemical-Biological Sciences, Institute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Ciudad Juárez 32310, Mexico.
Abraham Wall-MedranoDepartment of Health Sciences, Institute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Ciudad Juárez 32310, Mexico.ORCID 0000-0002-6196-3607
Emilio Álvarez-ParrillaDepartment of Chemical-Biological Sciences, Institute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Ciudad Juárez 32310, Mexico.ORCID 0000-0002-6162-8139
Imelda Olivas-ArmendárizDepartment of Physics and Mathematics, Institute of Engineering and Technology, Autonomous University of Ciudad Juarez, Ciudad Juárez 32310, Mexico.ORCID 0000-0003-2233-0310
Humberto Astiazaran-GarcíaDepartment of Nutrition, Food and Development Research Center A.C., Hermosillo 83304, Mexico.ORCID 0000-0002-2452-0057
Ramón E Robles-ZepedaDepartment of Chemical-Biological Sciences, University of Sonora, Hermosillo 83000, Mexico.ORCID 0000-0002-5279-4020
Laura A De la RosaDepartment of Chemical-Biological Sciences, Institute of Biomedical Sciences, Autonomous University of Ciudad Juarez, Ciudad Juárez 32310, Mexico.ORCID 0000-0003-2082-873X
Universidad Autónoma de Ciudad Juárez · MXUniversidad de Sonora · MX

Funding

Consejo Nacional de Ciencia y Tecnología CB-2015-1/254063
6 · The paper itself

Abstract

Tree nuts are rich in polar (phenolic compounds) and non-polar (tocols) antioxidants, with recognized effects in the prevention of diseases such as cancer. These biomolecules possess antiproliferative activity on cancer cells; however, the combined effect of both types of compounds has been scarcely studied, and this approach could give valuable information on the real anticancer potential of tree nuts. In the present study, the antiproliferative activity of pure tocols and phenolic compounds, tocol- and phenolic-rich extracts (TRE and PRE, respectively) from tree nuts and the extracts combinations, was evaluated in four cancer (HeLa, MCF7, PC3, A549) and one control (

Indexed as

NeoplasmsNutsHeLa CellsHumansPhenolsPlant ExtractsTocopherolsPhenolsPlant ExtractstocolTocopherolsantiproliferativebioactive compoundscancer cell linescell viabilityfood antioxidantspharmacological interactionspolyphenolstocopherolstocotrienols

Identifiers

PMID35630629
PMCPMC9143696
OpenAlexW4280502017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.