Evidence map›Paper›PMID 35630611›Full record

ArticleMolecules (Basel, Switzerland)2022

In Vitro and In Silico Evaluation of Cholinesterase Inhibition by Alkaloids Obtained from Branches of

Rochelly da Silva Mesquita, Andrii Kyrylchuk, Anton Cherednichenko, Ingrity Suelen Costa Sá, Lílian Macedo Bastos, Felipe Moura Araújo da Silva, Rita de Cássia Saraiva Nunomura, Andriy Grafov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Structural Bioinformatics Applied to Acetylcholinesterase Enzyme Inhibition.International journal of molecular sciences · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rochelly da Silva MesquitaAnalytical Central-Multidisciplinary Support Center-CAM, Federal University of Amazonas-UFAM, Manaus 69077-000, Amazonas, Brazil.
Andrii KyrylchukInstitute of Organic Chemistry, National Academy of Sciences-NAS, 5 Murmanska Str., 02660 Kyiv, Ukraine.ORCID 0000-0002-8845-5194
Anton CherednichenkoLatvian Institute of Organic Synthesis, Aizkraukles 21, 1006 Riga, Latvia.
Ingrity Suelen Costa SáAnalytical Central-Multidisciplinary Support Center-CAM, Federal University of Amazonas-UFAM, Manaus 69077-000, Amazonas, Brazil.
Lílian Macedo BastosAnalytical Central-Multidisciplinary Support Center-CAM, Federal University of Amazonas-UFAM, Manaus 69077-000, Amazonas, Brazil.
Felipe Moura Araújo da SilvaAnalytical Central-Multidisciplinary Support Center-CAM, Federal University of Amazonas-UFAM, Manaus 69077-000, Amazonas, Brazil.ORCID 0000-0002-1809-1372
Rita de Cássia Saraiva NunomuraAnalytical Central-Multidisciplinary Support Center-CAM, Federal University of Amazonas-UFAM, Manaus 69077-000, Amazonas, Brazil.
Andriy GrafovDepartment of Chemistry, University of Helsinki, A.I. Virtasen Aukio 1, 00560 Helsinki, Finland.ORCID 0000-0002-7387-3676

Funding

European Commission Horizon 2020-MSCA-RISE-2016-734759，acronym VAHVISTUSNational Council for Scientific and Technological Development CT-Amazônia Ed. No. 77/2013, proc. No. 408172/2013-4
6 · The paper itself

Abstract

Alkaloids are natural products known as ethnobotanicals that have attracted increasing attention due to a wide range of their pharmacological properties. In this study, cholinesterase inhibitors were obtained from branches of

Indexed as

AlkaloidsMenispermaceaeAcetylcholinesteraseButyrylcholinesteraseMolecular Docking SimulationAcetylcholinesteraseAlkaloidsButyrylcholinesteraseAbuta panurensisacetylcholinesterasealkaloidsbutyrylcholinesteraseinhibitory activitymolecular docking

Identifiers

PMID35630611
PMCPMC9144276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.