ArticleMolecules (Basel, Switzerland)2022
Green and Efficient Extraction of Polysaccharide and Ginsenoside from American Ginseng (
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- A comprehensive review on structural, chemical, and functional perspectives of dietary polysaccharide-driven gut microbiota modulation: Mechanisms and challenges.Biochemistry and biophysics reports · 2026Review
- Optimization of Bioactive Polysaccharide Extraction fromACS omega · 2026Article
- Machine learning-driven optimization of extraction process and development of quality standards for traditional Chinese medicine (TCM) formulae in primary liver cancer.RSC advances · 2026Article
- Extraction, structural characterization, chemical modification and anti-inflammatory activity of polysaccharides fromFrontiers in nutrition · 2026Article
- Research advances in red ginseng polysaccharides: preparation, structural characteristics and immunomodulatory effect.Frontiers in pharmacology · 2026Review
- Effects of alkaline salt stress on growth, physiological properties and medicinal components of clonal Glechoma longituba (Nakai) Kupr.BMC plant biology · 2024Article
- A Comprehensive Review on Deep Eutectic Solvents: Their Current Status and Potential for Extracting Active Compounds from Adaptogenic Plants.Molecules (Basel, Switzerland) · 2024Review
- Antitumor activity of Polygonatum sibiricum polysaccharides.Archives of pharmacal research · 2024Review
- Bioactive properties and gut microbiota modulation by date seed polysaccharides extracted using ultrasound-assisted deep eutectic solvent.Food chemistry: X · 2024Article
- Optimization of green deep eutectic solvent (DES) extraction ofRSC advances · 2023Article
- Exploring carbohydrate extraction from biomass using deep eutectic solvents: Factors and mechanisms.iScience · 2023Review
- American Ginseng for the Treatment of Alzheimer's Disease: A Review.Molecules (Basel, Switzerland) · 2023Review
- The Most Potent Natural Pharmaceuticals, Cosmetics, and Food Ingredients Isolated from Plants with Deep Eutectic Solvents.Journal of agricultural and food chemistry · 2023Review
- High-Value Bioconversion of Ginseng Extracts in Betaine-Based Deep Eutectic Solvents for the Preparation of Deglycosylated Ginsenosides.Foods (Basel, Switzerland) · 2023Article
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Abstract
In this study, a green and effective extraction method was proposed to extract two main compounds, ginsenosides and polysaccharides, from American ginseng by combining deep eutectic solvents (DESs) with aqueous two-phase systems. The factors of type of DESs, water content in DESs, the solid-liquid ratio, extraction temperature, and extraction time were studied in the solid-liquid extraction. Then, the aqueous two-phase system (DESs-ethylene oxide-propylene oxide (EOPO)) and salty solution exchange (EOPO-salty solution) was applied for the purification of polysaccharides. The content of the polysaccharides and ginsenosides were analyzed by the anthrone-sulfuric acid method and HPLC method, which showed that the extraction efficiency of deep eutectic solvents (DESs) was better than conventional methods. Moreover, the antioxidant activities of ginseng polysaccharides and their cytotoxicity were further assayed. The advantages of the current study are that, throughout the whole extraction process, we avoided the usage of an organic reagent. Furthermore, the separated green solvent DESs and EOPO could be recovered and reused for a next cycle. Thus, this study proposed a new, green and recyclable extraction method for extracting ginsenosides and polysaccharides from American ginseng.
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