Evidence map›Paper›PMID 35630416›Full record

ArticleMicroorganisms2022

Seroepidemiology of

Maria Alina Lupu, Rodica Lighezan, Ana Alexandra Paduraru, Angela Dragomir, Radu Pavel, Sebastian Grada, Alin Gabriel Mihu, Sorin Ursoniu, Tudor Rares Olariu

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Microorganisms · 2026
    Article
  2. Serological, Molecular, and Epidemiological Investigation ofTropical medicine and infectious disease · 2026
    Article
  3. Article
  4. Article
  5. Estimating the national seroprevalence ofEpidemiology and infection · 2025
    Article
  6. Life (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Risk Factors Associated withMicroorganisms · 2024
    Article
  14. Prevalence ofMicroorganisms · 2024
    Article
  15. Article
  16. Review
  17. Microorganisms · 2023
    Article
  18. The Medical Relevance ofMicroorganisms · 2023
    Review
  19. Life (Basel, Switzerland) · 2023
    Article
  20. Seroprevalence of Anti-Life (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Maria Alina LupuDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-1970-1934
Rodica LighezanDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Ana Alexandra PaduraruDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-6235-9076
Angela DragomirDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Radu PavelDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Sebastian GradaDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Alin Gabriel MihuDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Sorin UrsoniuDepartment of Functional Sciences, Center for Translational Research and Systems Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Tudor Rares OlariuDiscipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-1094-3729
Victor Babeș University of Medicine and Pharmacy Timișoara · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Toxoplasma gondii is estimated to infect 33% of blood donors worldwide, and seroprevalence varies widely between countries. We aimed to evaluate, for the first time, the seroprevalence and risk factors associated with T. gondii in blood donors from Western Romania. Methods: Serologic testing to demonstrate the presence of T. gondii antibodies was conducted in 1347 healthy blood donors. Risk factors for T. gondii infection were assessed through an epidemiological questionnaire. Results: The overall prevalence of T. gondii antibodies was 45.9%, with a significant age-associated increase (p < 0.001) from 32.6% in age group 18−25 years to 67.6% in age group 56−63 years. T. gondii seroprevalence decreased with increasing level of education, from 64.3% in individuals who graduated from elementary/middle school to 40.4% in those who graduated from University (p < 0.001). The multiple logistic regression analysis revealed that age, level of education and having pets (cats and/or dogs) were significantly associated with T. gondii infection. Conclusions: This study brings new and valuable data regarding the seroepidemiology of T. gondii infection in Romania. Our findings indicate a high prevalence of T. gondii antibodies in blood donors and may serve as a starting point for further epidemiological studies that should lead to implementation of prevention programs for toxoplasmosis.

Indexed as

antibodiesblood donorsepidemiologyrisk factorsRomaniaseroprevalenceToxoplasma gondii

Identifiers

PMID35630416
PMCPMC9143041
OpenAlexW4229074894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.