Evidence map›Paper›PMID 35630072›Full record

ReviewMedicina (Kaunas, Lithuania)2022

Water Dynamics in Cancer Cells: Lessons from Quasielastic Neutron Scattering.

Murillo L Martins, Heloisa N Bordallo, Eugene Mamontov

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Murillo L MartinsOak Ridge National Laboratory, Neutron Scattering Division, Oak Ridge, TN 37831, USA.
Heloisa N BordalloNiels Bohr Institute, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark.ORCID 0000-0003-0750-0553
Eugene MamontovOak Ridge National Laboratory, Neutron Scattering Division, Oak Ridge, TN 37831, USA.ORCID 0000-0002-5684-2675
Oak Ridge National Laboratory · USUniversity of Copenhagen · DK

Funding

United States Department of Energy DE-AC0205CH11231United States Department of Energy Fluid Interface Reactions, Structures and Transport (FIRST) CenterUT-Battelle DEAC05-00OR22725
6 · The paper itself

Abstract

The severity of the cancer statistics around the globe and the complexity involving the behavior of cancer cells inevitably calls for contributions from multidisciplinary areas of research. As such, materials science became a powerful asset to support biological research in comprehending the macro and microscopic behavior of cancer cells and untangling factors that may contribute to their progression or remission. The contributions of cellular water dynamics in this process have always been debated and, in recent years, experimental works performed with Quasielastic neutron scattering (QENS) brought new perspectives to these discussions. In this review, we address these works and highlight the value of QENS in comprehending the role played by water molecules in tumor cells and their response to external agents, particularly chemotherapy drugs. In addition, this paper provides an overview of QENS intended for scientists with different backgrounds and comments on the possibilities to be explored with the next-generation spectrometers under construction.

Indexed as

NeoplasmsWaterHumansNeutronsWatercancer cellsquasielastic neutron scatteringwater dynamics

Identifiers

PMID35630072
PMCPMC9145030
OpenAlexW4280536329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.