Evidence map›Paper›PMID 35630034›Full record

ArticleMedicina (Kaunas, Lithuania)2022

The Association between Iron-Deficiency Anemia (IDA) and Septic Arthritis (SA): The Real-World Data.

Cheng-Hung Chiang, Cheng-Yen Li, Kai-Chieh Hu, Yi-Hsiu Fu, Ching-Chih Chiu, Chia-Chun Hsia, Shu-Jui Kuo, Chih-Hung Hung

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cheng-Hung ChiangDepartment of Orthopedic Surgery, China Medical University Hospital, Taichung 404, Taiwan.ORCID 0000-0002-8365-1145
Cheng-Yen LiDepartment of Medical Education, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Kai-Chieh HuManagement Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan.
Yi-Hsiu FuDepartment of Education, China Medical University Hospital, Taichung 404, Taiwan.
Ching-Chih ChiuDepartment of Education, China Medical University Hospital, Taichung 404, Taiwan.ORCID 0000-0003-0248-2392
Chia-Chun HsiaDepartment of Education, China Medical University Hospital, Taichung 404, Taiwan.
Shu-Jui KuoDepartment of Orthopedic Surgery, China Medical University Hospital, Taichung 404, Taiwan.ORCID 0000-0002-2992-4608
Chih-Hung HungDepartment of Orthopedic Surgery, China Medical University Hospital, Taichung 404, Taiwan.
China Medical University · TWTaipei Veterans General Hospital · TW

Funding

China Medical University CMU109-MF-82China Medical University Hospital DMR-110-111China Medical University Hospital DMR-110-224China Medical University Hospital DMR-111-114China Medical University Hospital DMR-111-230Ministry of Science and Technology MOST 108-2221-E-039-006-MY3Ministry of Science and Technology MOST 108-2622-E-039-002-CC1Ministry of Science and Technology MOST 109-2314-B-039-018-MY3
6 · The paper itself

Abstract

Background and Objectives: Iron-deficiency anemia (IDA) could predispose the afflicted individuals to various infections and musculoskeletal disorders. This study attempted to investigate the association between IDA and septic arthritis (SA), a musculoskeletal disease. Materials and Methods: We investigated all the eligible subjects in the Taiwanese longitudinal health insurance database (LHID) between 2000 and 2012. Subjects with the diagnosis of IDA (International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM): 280) were allocated to the IDA cohort. The control subjects were randomly matched to every subject with IDA coding by age and sex at the 1:4 ratio. All of the recruited subjects were followed since the index date to the onset of SA (ICD-9-CM: 711.0), withdrawal from the insurance (including death), or 31 December 2013. Results: The cumulative incidence of SA was assessed. We showed that the cumulative incidence of SA was higher in the IDA cohort than in the control cohort (p-value < 0.0001). After adjustment of the comorbidities, the IDA patients had a 2.53-fold risk of SA compared to control subjects (aHR = 2.53, 95% CI = 1.89−3.38). Conclusions: IDA was associated with an increased risk of SA.

Indexed as

Anemia, Iron-DeficiencyArthritis, InfectiousCohort StudiesComorbidityHumansIncidenceiron-deficiency anemiaLHIDseptic arthritis

Identifiers

PMID35630034
PMCPMC9145831
OpenAlexW4225162856

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.