Evidence map›Paper›PMID 35629875›Full record

ArticleMetabolites2022

Intrapersonal Stability of Plasma Metabolomic Profiles over 10 Years among Women.

Oana A Zeleznik, Clemens Wittenbecher, Amy Deik, Sarah Jeanfavre, Julian Avila-Pacheco, Bernard Rosner, Kathryn M Rexrode, Clary B Clish, Frank B Hu, A Heather Eliassen

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. A plasma metabolomic fingerprint of moderate or severe hearing loss.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  7. Article
  8. Reproducibility of Plasma Metabolome over 1 Year in a Population-Based Cohort of Black Breast Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. An epidemiological introduction to human metabolomic investigations.Trends in endocrinology and metabolism: TEM · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Oana A ZeleznikChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-8705-1163
Clemens WittenbecherDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Amy DeikBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.ORCID 0000-0002-9687-0953
Sarah JeanfavreBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Julian Avila-PachecoBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Bernard RosnerChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Kathryn M RexrodeDivision of Women's Health, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Clary B ClishBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Frank B HuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
A Heather EliassenChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-3961-6609
Brigham and Women's Hospital · USBroad Institute · USHarvard University · US

Funding

Risk Factors for Ischemic Stroke in WomenR01HL088521 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REXRODE, KATHRYN M · 2008 to 2025
$9.9M
NHLBI NIH HHS R01 HL088521NIH HHS UM1 CA186107, P01 CA087969, R01 CA49449, R01 DK112940
6 · The paper itself

Abstract

In epidemiological studies, samples are often collected long before disease onset or outcome assessment. Understanding the long-term stability of biomarkers measured in these samples is crucial. We estimated within-person stability over 10 years of metabolites and metabolite features (

Indexed as

lipids and lipid-related metabolitespolar metabolitesunknown metabolite featureswithin-person stability

Identifiers

PMID35629875
PMCPMC9147746
OpenAlexW4224295109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.