ArticleMaterials (Basel, Switzerland)2022
The Characterization of Titanium Particles Released from Bone-Level Titanium Dental Implants: Effect of the Size of Particles on the Ion Release and Cytotoxicity Behaviour.
Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- The immune-microbe-metal triad: a vicious cycle driving biomaterial corrosion in the oral inflammatory microenvironment.Bioactive materials · 2027Review
- Detection of submicron titanium debris associated with peri-implantitis.Discover nano · 2026Review
- Beyond Biocompatibility: Immune Dysregulation, Oxidative Stress, and Tissue Intolerance Associated with Ti-6Al-4V Dental Implants-A Critical Review and Perspective.Antioxidants (Basel, Switzerland) · 2026Review
- Influence of Zirconium on the Microstructure, Selected Mechanical Properties, and Corrosion Resistance of TiMaterials (Basel, Switzerland) · 2024Article
- Emission and Migration of Nanoscale Particles during Osseointegration and Disintegration of Dental Implants in the Clinic and Experiment and the Influence on Cytokine Production.International journal of molecular sciences · 2023Article
- Effects of Hypochlorous Acid and Hydrogen Peroxide Treatment on Bacterial Disinfection Treatments in Implantoplasty Procedures.Materials (Basel, Switzerland) · 2023Article
- Diffusion of Vanadium Ions in Artificial Saliva and Its Elimination from the Oral Cavity by Pharmacological Compounds Present in Mouthwashes.Biomolecules · 2022Article
- Effect of the Size of Titanium Particles Released from Dental Implants on Immunological Response.International journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many studies are being carried out on the particles released during the implantoplasty process in the machining of dental implants to remove bacterial biofilms. However, there are no studies on the release of particles produced by the insertion of bone-level dental implants due to the high compressive frictional loads between the rough titanium implant and the bone tissue. This paper aims to characterize the released particles and determine the release of titanium ions into the physiological environment and their cytocompatibility. For this purpose, 90 dental implants with a neck diameter of 4 mm and a torque of 22 Ncm were placed in 7 fresh cow ribs. The placement was carried out according to the established protocols. The implants had a roughness Ra of 1.92 μm. The arrangement of the particles in the bone tissue was studied by micro-CT, and no particle clusters were observed. The different granulometries of 5, 15, and 30 μm were obtained; the specific surface area was determined by laser diffraction; the topography was determined by scanning electron microcopy; and the particles were chemically analysed by X-ray energy microanalysis. The residual stresses of the particles were obtained by X-ray diffraction using the Bragg-Bentano configuration. The release of titanium ions to the physiological medium was performed using ICP-MS at 1, 3, 7, 14, and 21 days. The cytocompatibility of the particles with HFF-1 fibroblast and SAOS-2 osteoblast cultures was characterized. The results showed that the lowest specific surface area (0.2109 m
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