Evidence map›Paper›PMID 35629422›Full record

ArticleLife (Basel, Switzerland)2022

Human Amniotic Mesenchymal Stem Cells and Fibroblasts Accelerate Wound Repair of Cystic Fibrosis Epithelium.

Elisa Beccia, Valeria Daniello, Onofrio Laselva, Giorgia Leccese, Michele Mangiacotti, Sante Di Gioia, Gianfranco La Bella, Lorenzo Guerra, Maria Matteo, Antonella Angiolillo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. International journal of molecular sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Elisa BecciaDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Valeria DanielloDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Onofrio LaselvaDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
Giorgia LecceseDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0001-9754-4693
Michele MangiacottiS.C. di Radioterapia Oncologica, Policlinico Riuniti, Azienda Ospedaliero-Universitaria, 71122 Foggia, Italy.
Sante Di GioiaDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0001-7246-5622
Gianfranco La BellaIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata (IZSPB), 71121 Foggia, Italy.ORCID 0000-0003-3557-1439
Lorenzo GuerraDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, 70125 Bari, Italy.
Maria MatteoDepartment of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.
Antonella AngiolilloDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-0158-3039
Massimo ConeseDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0003-3465-6641
University of Foggia · ITIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata · ITOspedali Riuniti di Foggia · ITUniversity of Bari Aldo Moro · ITUniversity of Molise · IT

Funding

University of Foggia DR n. 392-2019, Prot. N. 13546- VII/1, 01/04/2019
6 · The paper itself

Abstract

Cystic fibrosis (CF) airways are affected by a deranged repair of the damaged epithelium resulting in altered regeneration and differentiation. Previously, we showed that human amniotic mesenchymal stem cells (hAMSCs) corrected base defects of CF airway epithelial cells via connexin (CX)43-intercellular gap junction formation. In this scenario, it is unknown whether hAMSCs, or fibroblasts sharing some common characteristics with MSCs, can operate a faster repair of a damaged airway epithelium. A tip-based scratch assay was employed to study wound repair in monolayers of CFBE14o- cells (CFBE, homozygous for the

Indexed as

airway epitheliumcell proliferationcystic fibrosisfibroblastshuman mesenchymal stem cellswound repair

Identifiers

PMID35629422
PMCPMC9144497
OpenAlexW4280501491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.