Evidence map›Paper›PMID 35629417›Full record

ArticleLife (Basel, Switzerland)2022

Expression Analysis of Genes Involved in Transport Processes in Mice with MPTP-Induced Model of Parkinson's Disease.

Margarita M Rudenok, Maria I Shadrina, Elena V Filatova, Ivan N Rybolovlev, Maxim S Nesterov, Denis A Abaimov, Ruslan A Ageldinov, Anna A Kolacheva, Michael V Ugrumov, Petr A Slominsky and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  6. Analysis ofBioMed research international · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Margarita M RudenokInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.ORCID 0000-0002-6524-9101
Maria I ShadrinaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.
Elena V FilatovaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.
Ivan N RybolovlevInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.
Maxim S NesterovScientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia, Svetlye Gory Village, Post Office Otradnoe, Krasnogorsk District, 143442 Moscow, Russia.
Denis A AbaimovThe Research Centre of Neurology, 80, Volokolamskoye Shosse, 125367 Moscow, Russia.ORCID 0000-0001-6888-3223
Ruslan A AgeldinovScientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia, Svetlye Gory Village, Post Office Otradnoe, Krasnogorsk District, 143442 Moscow, Russia.
Anna A KolachevaKoltsov Institute of Developmental Biology, Russian Academy of Sciences, 26 Vavilov Street, 119334 Moscow, Russia.ORCID 0000-0003-1495-3067
Michael V UgrumovKoltsov Institute of Developmental Biology, Russian Academy of Sciences, 26 Vavilov Street, 119334 Moscow, Russia.
Petr A SlominskyInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.
Anelya Kh AlievaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", 2 Kurchatova Sq., 123182 Moscow, Russia.ORCID 0000-0002-6200-4491
Kurchatov Institute · RUFederal Medical-Biological Agency · RUKoltzov Institute of Developmental Biology · RUResearch Center of Neurology · RU

Funding

Russian Science Foundation 20-15-00262the IDB RAS Government basic research program 2022 № 0088-2021-0018the Ministry of Science and Higher Education of the Russian Federation 075-15-2021-135
6 · The paper itself

Abstract

Processes of intracellular and extracellular transport play one of the most important roles in the functioning of cells. Changes to transport mechanisms in a neuron can lead to the disruption of many cellular processes and even to cell death. It was shown that disruption of the processes of vesicular, axonal, and synaptic transport can lead to a number of diseases of the central nervous system, including Parkinson's disease (PD). Here, we studied changes in the expression of genes whose protein products are involved in the transport processes (

Indexed as

early diagnosticsgene expressionmolecular mechanismsMPTPneurodegenerationneurological diseasesParkinson’s diseasetransport processes

Identifiers

PMID35629417
PMCPMC9146539
OpenAlexW4280572678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.