Evidence map›Paper›PMID 35629416›Full record

ReviewLife (Basel, Switzerland)2022

Nanoparticles: Synthesis and Their Role as Potential Drug Candidates for the Treatment of Parasitic Diseases.

Hammad Ur Rehman Bajwa, Muhammad Kasib Khan, Zaheer Abbas, Roshan Riaz, Tauseef Ur Rehman, Rao Zahid Abbas, Muhammad Tahir Aleem, Asghar Abbas, Mashal M Almutairi, Fahdah Ayed Alshammari and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Green synthesis of AuNPs usingRSC advances · 2025
    Article
  4. Article
  5. Unlocking the Hidden Potential ofInternational journal of molecular sciences · 2025
    Article
  6. In Vitro Effects of Vanadate Erbium/Silver Oxide (ErVOVeterinary medicine and science · 2025
    Article
  7. Platinum Group Metals against Parasites: State of the Art and Future Perspectives.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Review
  8. Article
  9. Article
  10. Nanoarchitectonics for synergistic activity of multimetallic nanohybrids as a possible approach for antimicrobial resistance (AMR).Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Review
  11. Review
  12. Review
  13. Article
  14. Iranian journal of parasitology
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 4 countries.

Hammad Ur Rehman BajwaDepartment of Parasitology, Ankara University, Ankara 06100, Turkey.ORCID 0000-0001-6908-7659
Muhammad Kasib KhanDepartment of Parasitology, University of Agriculture, Faisalabad 38040, Pakistan.ORCID 0000-0001-6050-4321
Zaheer AbbasDepartment of Parasitology, University of Agriculture, Faisalabad 38040, Pakistan.
Roshan RiazDepartment of Animal Nutrition and Nutritional Diseases, Ankara University, Ankara 06100, Turkey.
Tauseef Ur RehmanDepartment of Parasitology, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Rao Zahid AbbasDepartment of Parasitology, University of Agriculture, Faisalabad 38040, Pakistan.
Muhammad Tahir AleemMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Asghar AbbasFaculty of Veterinary and Animal Sciences, MNS-University of Agriculture Multan, Multan 60650, Pakistan.
Mashal M AlmutairiDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Fahdah Ayed AlshammariCollege of Sciences and Literature Microbiology, Arar Northern Border University, Arar 73211, Saudi Arabia.
Yasser AlraeyDepartment of Clinical Laboratory Sciences, Central Research Laboratory, College of Applied Medical Sciences, King Khalid University, Abha 62217, Saudi Arabia.ORCID 0000-0002-5809-7525
Abdulaziz AlouffiKing Abdulaziz City for Science and Technology, Riyadh 12354, Saudi Arabia.ORCID 0000-0001-8863-3870
University of Faisalabad · PKAnkara University · TRIslamia University of Bahawalpur · PKKing Abdulaziz City for Science and Technology · SAKing Khalid University · SAKing Saud University · SANanjing Agricultural University · CNNorthern Border University · SAThe University of Agriculture, Peshawar · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protozoa, helminths and ectoparasites are the major groups of parasites distributed worldwide. Currently, these parasites are treated with chemotherapeutic antiprotozoal drugs, anti-helminthic and anti-ectoparasitic agents, but, with the passage of time, resistance to these drugs has developed due to overuse. In this scenario, nanoparticles are proving to be a major breakthrough in the treatment and control of parasitic diseases. In the last decade, there has been enormous development in the field of nanomedicine for parasitic control. Gold and silver nanoparticles have shown promising results in the treatments of various types of parasitic infections. These nanoparticles are synthesized through the use of various conventional and molecular technologies and have shown great efficacy. They work in different ways, that include damaging the parasite membrane, DNA (Deoxyribonucleic acid) disruption, protein synthesis inhibition and free-radical formation. These agents are effective against intracellular parasites as well. Other nanoparticles, such as iron, nickel, zinc and platinum, have also shown good results in the treatment and control of parasitic infections. It is hoped that this research subject will become the future of modern drug development. This review summarizes the methods that are used to synthesize nanoparticles and their possible mechanisms of action against parasites.

Indexed as

mechanisms of actionnanoparticlesparasite controlsynthesis

Identifiers

PMID35629416
PMCPMC9145985
OpenAlexW4280564689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.