Evidence map›Paper›PMID 35629388›Full record

ArticleLife (Basel, Switzerland)2022

Role of Uncoupling Protein 2 Gene Polymorphisms on the Risk of Ischemic Stroke in a Sardinian Population.

Rosita Stanzione, Maria Cotugno, Maurizio Forte, Franca Bianchi, Simona Marchitti, Nicole Piera Palomba, Teresa Esposito, Bastianina Zanda, Alessandra Sanna, Speranza Rubattu

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Association ofBalkan journal of medical genetics : BJMG · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rosita StanzioneIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.
Maria CotugnoIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.
Maurizio ForteIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.ORCID 0000-0003-0739-0534
Franca BianchiIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.
Simona MarchittiIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.
Nicole Piera PalombaIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.ORCID 0000-0001-6240-9272
Teresa EspositoIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.ORCID 0000-0002-7879-8441
Bastianina ZandaStroke Unit, SS. Annunziata Hospital, 07100 Sassari, Italy.
Alessandra SannaStroke Unit, SS. Annunziata Hospital, 07100 Sassari, Italy.
Speranza RubattuIRCCS Neuromed, Località Camerelle, 86077 Pozzilli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mitochondrial uncoupling protein 2 (UCP2) acts as an anion transporter and as an antioxidant factor able to reduce the reactive oxygen species level. Based on its effects, UCP2 prevents the membrane lipids, proteins, and DNA damage while preserving normal cellular functions. Many variants have been identified within the human

Indexed as

genetic associationischemic strokeSardiniansuncoupling protein 2vascular disease

Identifiers

PMID35629388
PMCPMC9147365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.