Evidence map›Paper›PMID 35629253›Full record

ReviewJournal of personalized medicine2022

Tailored Treatment Options for Cerebral Cavernous Malformations.

Jessa E Hoffman, Blake Wittenberg, Brent Morel, Zach Folzenlogen, David Case, Christopher Roark, Samy Youssef, Joshua Seinfeld

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Stereotactic radiosurgery in the treatment of pediatric cerebral cavernous malformations: a systematic review and meta-analysis of outcomes and safety.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jessa E HoffmanDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.
Blake WittenbergDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.
Brent MorelDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0002-4775-9466
Zach FolzenlogenDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.
David CaseDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.
Christopher RoarkDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.
Samy YoussefDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.
Joshua SeinfeldDepartment of Neurosurgery, University of Colorado, Aurora, CO 80045, USA.
University of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis and treatment of cerebral cavernous malformations (CCMs), or cavernomas, continues to evolve as more data and treatment modalities become available. Intervention is necessary when a lesion causes symptomatic neurologic deficits, seizures, or has high risk of continued hemorrhage. Future medical treatment directions may specifically target the pathogenesis of these lesions. This review highlights the importance of individualized treatment plans based on specific CCM characteristics.

Indexed as

cavernomasCCMscerebral cavernous malformations

Identifiers

PMID35629253
PMCPMC9147523
OpenAlexW4280646446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.