ArticleJournal of personalized medicine2022
Enhanced Risk of Osteoporotic Fracture in Patients with Sarcopenia: A National Population-Based Study in Taiwan.
Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Global epidemiological features and impact of osteosarcopenia: A comprehensive meta-analysis and systematic review.Journal of cachexia, sarcopenia and muscle · 2024Pooled it
- Sarcopenia, its components and fracture risk in people living with human immunodeficiency virus.Revista da Associacao Medica Brasileira (1992) · 2026Article
- A w-ACT model for sarcopenia among community-dwelling older adults based on National Basic Public Health Services: development and validation study.Frontiers in public health · 2025Article
- Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate muscle atrophy via the miR-132-3p/FoxO3 axis.Journal of orthopaedic translation · 2024Article
- Sarcopenia definitions and their association with fracture risk in older Swedish women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Risk of Fractures, Repeated Fractures and Osteoporotic Fractures among Patients with Hemophilia in Taiwan: A 14-Year Population-Based Cohort Study.International journal of environmental research and public health · 2022Article
- Prevalence and Risk Factors of Sarcopenia in Community-Dwelling Older Adults: A Cross-Sectional Study With Nutritional Assessment.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
Sarcopenia is a progressive and generalized skeletal muscle disorder associated with poor health outcomes in older adults. However, its association with the risk of fracture risk is yet to be clarified. Therefore, this study aimed to assess the incidence and consequence of osteoporosis-related fractures among patients with sarcopenia in Taiwan. A retrospective, population-based study on 616 patients with sarcopenia, aged >40 years, and 1232 individuals without sarcopenia was conducted to evaluate claims data from Taiwan’s National Health Insurance Research Database collected in the period January 2000−December 2013. The incidence rate of osteoporosis-related fracture was 18.13 and 14.61 per 1000 person years in the patients with sarcopenia and comparison cohort, respectively. Patients with sarcopenia had a greater osteoporotic fracture risk (adjusted hazard ratio [HR] 2.11; 95% confidence interval [CI] 1.47−3.04) after correcting for possible confounding. Additionally, females showed statistically significant correlations of sarcopenia with osteoporosis-related fracture risk (HR 1.53; CI 0.83−2.8 for males and HR 2.40, CI 1.51−3.81 for females). During this retrospective study on the fracture risk in Taiwan, an adverse impact of sarcopenia was observed, which substantiates the need to work toward sarcopenia prevention and interventions to reverse fracture susceptibility in patients with sarcopenia.
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