Evidence map›Paper›PMID 35629166›Full record

ArticleJournal of personalized medicine2022

Association of Genetic Polymorphisms with Complications of Implanted LVAD Devices in Patients with Congestive Heart Failure: A Kazakhstani Study.

Madina R Zhalbinova, Saule E Rakhimova, Ulan A Kozhamkulov, Gulbanu A Akilzhanova, Galina K Kaussova, Kenes R Akilzhanov, Yuriy V Pya, Joseph H Lee, Makhabbat S Bekbossynova, Ainur R Akilzhanova

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Madina R ZhalbinovaNational Laboratory Astana, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0001-9704-8913
Saule E RakhimovaNational Laboratory Astana, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0002-8245-2400
Ulan A KozhamkulovNational Laboratory Astana, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0002-9782-7631
Gulbanu A AkilzhanovaSemey Medical University, Pavlodar Branch, Pavlodar 140000, Kazakhstan.
Galina K KaussovaKazakhstan Medical University "KSPH", Almaty 050000, Kazakhstan.
Kenes R AkilzhanovSemey Medical University, Pavlodar Branch, Pavlodar 140000, Kazakhstan.
Yuriy V PyaNational Research Cardiac Surgery Center, Nur-Sultan 010000, Kazakhstan.
Joseph H LeeSergievsky Center, Taub Institute, Columbia University Irving Medical Centerx, 630 W, New York, NY 10032, USA.ORCID 0000-0002-2000-4821
Makhabbat S BekbossynovaNational Research Cardiac Surgery Center, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0003-2834-617X
Ainur R AkilzhanovaNational Laboratory Astana, Nazarbayev University, Nur-Sultan 010000, Kazakhstan.ORCID 0000-0001-6161-8355
L. N. Gumilyov Eurasian National University · KZNazarbayev University · KZSemey Medical University · KZColumbia University Irving Medical Center · USKazakhstan Medical University · KZ

Funding

Ministry of Education and Science of the Republic of Kazakhstan AP09563474
6 · The paper itself

Abstract

The left ventricular assist device (LVAD) is one of the alternative treatments for heart failure (HF) patients. However, LVAD support is followed by thrombosis, and bleeding complications which are caused by high non-physiologic shear stress and antithrombotic/anticoagulant therapy. A high risk of complications occurs in the presence of the genotype polymorphisms which are involved in the coagulation system, hemostasis function and in the metabolism of the therapy. The aim of the study was to investigate the influence of single-nucleotide polymorphisms (SNP) in HF patients with LVAD complications. We analyzed 21 SNPs in HF patients (

Indexed as

bleedinggenotypeheart failureleft ventricular assist device (LVAD)personalized medicinepolymorphismthrombosis

Identifiers

PMID35629166
PMCPMC9143784
OpenAlexW4225425672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.