Evidence map›Paper›PMID 35629128›Full record

ReviewJournal of personalized medicine2022

Asthma-COPD Overlap Syndrome: Recent Insights and Unanswered Questions.

Evangelia Fouka, Andriana I Papaioannou, Georgios Hillas, Paschalis Steiropoulos

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. The Evolving Landscape of COPD Typization.Medicina (Kaunas, Lithuania) · 2026
    Review
  4. Genome-wide Association Study IdentifiesAllergy, asthma & immunology research · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Asthma and respiratory comorbidities.The Journal of allergy and clinical immunology · 2025
    Review
  11. Plasma Levels of CXCL9 and MCP-3 are Increased in Asthma-COPD Overlap (ACO) Patients.International journal of chronic obstructive pulmonary disease · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Evangelia FoukaPulmonary Medicine Department, Aristotle University of Thessaloniki, G Papanikolaou Hospital, 57010 Thessaloniki, Greece.
Andriana I Papaioannou2nd Department of Respiratory Medicine, "Attikon" Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Georgios Hillas5th Pulmonary Department, "Sotiria" Chest Diseases Hospital, 11527 Athens, Greece.
Paschalis SteiropoulosDepartment of Respiratory Medicine, Medical School, University General Hospital Dragana, Democritus University of Thrace, 68100 Alexandroupolis, Greece.ORCID 0000-0001-7121-6253
Aristotle University of Thessaloniki · GRDemocritus University of Thrace · GRNational and Kapodistrian University of Athens · GRSotiria General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term asthma-COPD overlap (ACO) has been used to identify a heterogeneous condition in which patients present with airflow limitation that is not completely reversible and clinical and inflammatory features of both asthma and chronic obstructive pulmonary disease (COPD). ACO diagnosis may be difficult in clinical practice, while controversy still exists regarding its definition, pathophysiology, and impact. Patients with ACO experience a greater disease burden compared to patients with asthma or COPD alone, but in contrast they show better response to inhaled corticosteroid treatment than other COPD phenotypes. Current management recommendations focus on defining specific and measurable treatable clinical traits, according to disease phenotypes and underlying biological mechanisms for every single patient. In this publication, we review the current knowledge on definition, pathophysiology, clinical characteristics, and management options of ACO.

Indexed as

ACOasthmabiomarkersCOPDdefinitiongeneticspathophysiologyprognosistreatable traits

Identifiers

PMID35629128
PMCPMC9146831
OpenAlexW4225123336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.