Evidence map›Paper›PMID 35629109›Full record

ArticleJournal of personalized medicine2022

The Detrimental Clinical Associations of Anxiety and Depression with Difficult Asthma Outcomes.

Wei Chern Gavin Fong, Ishmail Rafiq, Matthew Harvey, Sabina Stanescu, Ben Ainsworth, Judit Varkonyi-Sepp, Heena Mistry, Mohammed Aref Kyyaly, Clair Barber, Anna Freeman and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Wei Chern Gavin FongSchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.ORCID 0000-0003-2546-156X
Ishmail RafiqFaculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.ORCID 0000-0002-5750-2648
Matthew HarveyNIHR Biomedical Research Centre, University Hospitals Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Sabina StanescuDepartment of Psychology, University of Southampton, Southampton SO17 1BJ, UK.ORCID 0000-0003-0792-8939
Ben AinsworthNIHR Biomedical Research Centre, University Hospitals Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0002-5098-1092
Judit Varkonyi-SeppSchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.
Heena MistrySchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.
Mohammed Aref KyyalySchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.ORCID 0000-0002-1684-9207
Clair BarberNIHR Biomedical Research Centre, University Hospitals Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0001-5335-5129
Anna FreemanSchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.
Tom WilkinsonSchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.
Ratko DjukanovicSchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.
Paddy DennisonNIHR Biomedical Research Centre, University Hospitals Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Hans Michael HaitchiSchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.ORCID 0000-0001-8603-302X
Ramesh J KurukulaaratchySchool of Clinical and Experimental Sciences, University of Southampton, Southampton SO16 6YD, UK.
University of Southampton · GBIsle of Wight NHS Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Bath · GB

Funding

AAIR Charity charitable grantMedical Research Council G0802804MRF_ MRF-009-0003-RG-HAITCNovartis non-promotional grant
6 · The paper itself

Abstract

Difficult asthma describes asthma in which comorbidities, inadequate treatment, suboptimal inhaler technique and/or poor adherence impede good asthma control. The association of anxiety and depression with difficult asthma outcomes (exacerbations, hospital admissions, asthma control, etc.) is unclear. This study assessed the clinical associations of anxiety and depression with difficult asthma outcomes in patients with a specialist diagnosis of difficult asthma. Using real-world data, we retrospectively phenotyped patients from the Wessex Asthma Cohort of Difficult Asthma (

Indexed as

anxiety disordersasthmacohort studiesmental healthmood disorders

Identifiers

PMID35629109
PMCPMC9142921
OpenAlexW4224996778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.