Evidence map›Paper›PMID 35629095›Full record

ReviewJournal of personalized medicine2022

The Promise of Nanotechnology in Personalized Medicine.

Maha Ali Alghamdi, Antonino N Fallica, Nicola Virzì, Prashant Kesharwani, Valeria Pittalà, Khaled Greish

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 236 citations in OpenAlex.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Maha Ali AlghamdiDepartment of Biotechnology, College of science, Taif University, Taif 21974, Saudi Arabia.ORCID 0000-0002-5424-388X
Antonino N FallicaDepartment of Drug and Health Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0003-1899-8414
Nicola VirzìDepartment of Drug and Health Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0002-3273-8507
Prashant KesharwaniDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0002-0890-769X
Valeria PittalàDepartment of Drug and Health Sciences, University of Catania, 95125 Catania, Italy.ORCID 0000-0003-1856-0308
Khaled GreishDepartment of Molecular Medicine, Princess Al-Jawhara Centre for Molecular Medicine, College of Medicine and Medical Sciences, Arabian Gulf University, Manama 329, Bahrain.ORCID 0000-0002-0787-7070
University of Catania · ITArabian Gulf University · BHJamia Hamdard · INTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both personalized medicine and nanomedicine are new to medical practice. Nanomedicine is an application of the advances of nanotechnology in medicine and is being integrated into diagnostic and therapeutic tools to manage an array of medical conditions. On the other hand, personalized medicine, which is also referred to as precision medicine, is a novel concept that aims to individualize/customize therapeutic management based on the personal attributes of the patient to overcome blanket treatment that is only efficient in a subset of patients, leaving others with either ineffective treatment or treatment that results in significant toxicity. Novel nanomedicines have been employed in the treatment of several diseases, which can be adapted to each patient-specific case according to their genetic profiles. In this review, we discuss both areas and the intersection between the two emerging scientific domains. The review focuses on the current situation in personalized medicine, the advantages that can be offered by nanomedicine to personalized medicine, and the application of nanoconstructs in the diagnosis of genetic variability that can identify the right drug for the right patient. Finally, we touch upon the challenges in both fields towards the translation of nano-personalized medicine.

Indexed as

nanomedicinepersonalized medicinepharmacogeneticspharmacokinetics

Identifiers

PMID35629095
PMCPMC9142986
OpenAlexW4224314779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.