Evidence map›Paper›PMID 35629052›Full record

ArticleJournal of clinical medicine2022

The Incidence and Impact of In-Hospital Bleeding in Patients with Acute Coronary Syndrome during the COVID-19 Pandemic.

Roberto Licordari, Alessandro Sticchi, Filippo Mancuso, Alessandro Caracciolo, Saverio Muscoli, Fortunato Iacovelli, Rossella Ruggiero, Alessandra Scoccia, Valeria Cammalleri, Marco Pavani and 32 more

Open access · goldAbstract read
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Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 17 institutions in 1 country.

Roberto LicordariDepartment of Clinical and Experimental Medicine, Policlinic "G Martino", University of Messina, 98124 Messina, Italy.ORCID 0000-0003-3185-9240
Alessandro SticchiGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Filippo MancusoDepartment of Clinical and Experimental Medicine, Policlinic "G Martino", University of Messina, 98124 Messina, Italy.ORCID 0000-0003-3913-6485
Alessandro CaraccioloDepartment of Clinical and Experimental Medicine, Policlinic "G Martino", University of Messina, 98124 Messina, Italy.
Saverio MuscoliDepartment of Cardiovascular Disease, Tor Vergata University, 00133 Rome, Italy.ORCID 0000-0002-4037-7561
Fortunato IacovelliDivision of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, 072006 Bari, Italy.ORCID 0000-0002-4620-678X
Rossella RuggieroGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Alessandra ScocciaGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Valeria CammalleriDepartment of Cardiovascular Disease, Tor Vergata University, 00133 Rome, Italy.ORCID 0000-0001-5374-8125
Marco PavaniDepartment of Cardiology, Ospedale Civile SS Annunziata, 12038 Savigliano, Italy.ORCID 0000-0003-4581-6700
Marco LoffiDepartment of Cardiology, Ospedale di Cremona, 26100 Cremona, Italy.
Domenico ScordinoDivision of Cardiology, Aurelia Hospital, 00165 Rome, Italy.
Jayme FerroU.O.S.D. Cardiologia-Laboratorio di Emodinamica, Dipartimento di Emergenza, Rianimazione e Anestesia, ASST Lariana, Ospedale S. Anna, 22100 Como, Italy.
Andrea RognoniDepartment of Cardiology, Azienda Ospedaliero-Universitaria Maggiore della Carità, 28100 Novara, Italy.
Andrea BuonoClinical and Interventional Cardiology Unit, Istituto Clinico Sant'Ambrogio, 20149 Milan, Italy.ORCID 0000-0001-5767-7416
Stefano NavaDivision of Invasive Cardiology, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy.
Stefano AlbaniDepartment of Cardiology, Mauriziano Hospital, 10128 Turin, Italy.ORCID 0000-0002-1407-6087
Iginio ColaioriAzienda Unità Sanitaria Locale, IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Filippo ZilioU.O.C. Cardiologia, Ospedale Santa Chiara, 38121 Trento, Italy.ORCID 0000-0002-7217-4961
Marco BorghesiU.O.C. Cardiologia, Ospedale Santa Chiara, 38121 Trento, Italy.ORCID 0000-0003-2236-2769
Valentina RegazzoniDepartment of Cardiology, Ospedale di Cremona, 26100 Cremona, Italy.
Stefano BenenatiDipartimento CardioToracoVascolare, Ospedale Policlinico San Martino IRCCS, 16132 Genoa, Italy.ORCID 0000-0001-9669-4278
Fabio PescetelliDipartimento CardioToracoVascolare, Ospedale Policlinico San Martino IRCCS, 16132 Genoa, Italy.
Vincenzo De MarzoDipartimento CardioToracoVascolare, Ospedale Policlinico San Martino IRCCS, 16132 Genoa, Italy.ORCID 0000-0002-8031-9761
Antonia MannariniDivision of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, 072006 Bari, Italy.
Francesco SpioneDivision of University Cardiology, Cardiothoracic Department, Policlinico University Hospital, 072006 Bari, Italy.
Doronzo BaldassarreDepartment of Cardiology, Ospedale Civile SS Annunziata, 12038 Savigliano, Italy.
Michele De BenedictisDepartment of Cardiology, Ospedale Civile SS Annunziata, 12038 Savigliano, Italy.
Roberto BonmassariU.O.C. Cardiologia, Ospedale Santa Chiara, 38121 Trento, Italy.
Gian Battista DanziDepartment of Cardiology, Ospedale di Cremona, 26100 Cremona, Italy.ORCID 0000-0003-0897-8006
Mario GalliU.O.S.D. Cardiologia-Laboratorio di Emodinamica, Dipartimento di Emergenza, Rianimazione e Anestesia, ASST Lariana, Ospedale S. Anna, 22100 Como, Italy.
Alfonso IelasiClinical and Interventional Cardiology Unit, Istituto Clinico Sant'Ambrogio, 20149 Milan, Italy.ORCID 0000-0002-5982-1669
Giuseppe MusumeciDepartment of Cardiology, Mauriziano Hospital, 10128 Turin, Italy.
Fabrizio TomaiDivision of Cardiology, Aurelia Hospital, 00165 Rome, Italy.
Vincenzo PasceriDepartment of Cardiology, San Filippo Neri Roma, 00135 Rome, Italy.
Italo PortoDipartimento CardioToracoVascolare, Ospedale Policlinico San Martino IRCCS, 16132 Genoa, Italy.
Giuseppe PattiDepartment of Cardiology, Azienda Ospedaliero-Universitaria Maggiore della Carità, 28100 Novara, Italy.ORCID 0000-0002-5404-3968
Gianluca CampoCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, 30010 Cona, Italy.
Antonio ColomboGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Antonio MicariDepartment of Clinical and Experimental Medicine, Policlinic "G Martino", University of Messina, 98124 Messina, Italy.
Francesco GianniniGVM Care & Research, Maria Cecilia Hospital, 48033 Cotignola, Italy.
Francesco CostaDepartment of Clinical and Experimental Medicine, Policlinic "G Martino", University of Messina, 98124 Messina, Italy.ORCID 0000-0002-3097-2834
University of Messina · ITMaria Cecilia Hospital · ITOspedale Policlinico San Martino · ITIstituti Ospitalieri di Cremona · ITOspedale Santa Chiara · ITOspedale SS. Annunziata · ITA. O. Ordine Mauriziano di Torino · ITAurelia Hospital · ITAzienda Socio Sanitaria Territoriale Lariana · ITIstituto Clinico Sant'Ambrogio · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Rome Tor Vergata · ITArcispedale Sant'Anna · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITOspedale San Filippo Neri · ITSaint Camillus International University of Health and Medical Sciences · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic increased the complexity of the clinical management and pharmacological treatment of patients presenting with an Acute Coronary Syndrome (ACS).

aimto explore the incidence and prognostic impact of in-hospital bleeding in patients presenting with ACS before and during the COVID-19 pandemic.

methodsWe evaluated in-hospital Thrombolysis In Myocardial Infarction (TIMI) major and minor bleeding among 2851 patients with ACS from 17 Italian centers during the first wave of the COVID-19 pandemic (i.e., March-April 2020) and in the same period in the previous two years.

resultsThe incidence of in-hospital TIMI major and minor bleeding was similar before and during the COVID-19 pandemic. TIMI major or minor bleeding was associated with a significant threefold increase in all-cause mortality, with a similar prognostic impact before and during the COVID-19 pandemic.

conclusionsthe incidence and clinical impact of in-hospital bleeding in ACS patients was similar before and during the COVID-19 pandemic. We confirmed a significant and sizable negative prognostic impact of in-hospital bleeding in ACS patients.

Indexed as

acute coronary syndrome (ACS)bleedingCOVID-19in-hospital outcomesmyocardial infarction (MI)

Identifiers

PMID35629052
PMCPMC9146584
OpenAlexW4281264276

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.