ReviewJournal of clinical medicine2022
Blood Transfusion Reactions-A Comprehensive Review of the Literature including a Swiss Perspective.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Efficacy and Outcomes of Oxidized Regenerated Cellulose (ORC) in Total Joint Arthroplasty (TJA): A Systematic Review and Meta-Analysis.The Iowa orthopaedic journal · 2026Pooled it
- Efficacy and safety of topical versus intravenous tranexamic acid in spinal surgery: a systematic review and meta-analysis.BMC surgery · 2025Pooled it
- Targeting innovative therapeutic approaches to the hallmarks of aging to combat Alzheimer's disease.Neural regeneration research · 2026Article
- Treatment of Acute Hemolytic Transfusion Reaction due to ABO-Incompatible Red Blood Cell Transfusion: A Case Report, Review of the Literature and Recommendation.Journal of clinical apheresis · 2026Review
- Validation of the Spanish Blood Donation Knowledge Questionnaire (BDKQ-Spain) Through University-School Partnerships.Healthcare (Basel, Switzerland) · 2026Article
- Plasma-based strategies for systemic rejuvenation: critical perspectives on clinical translation.GeroScience · 2026Review
- Perioperative Anemia, Transfusion Practices, and Patient Blood Management: Lessons from the COVID-19 Pandemic.Hematology reports · 2026Review
- [A proposed decision-making algorithm for discrepancies between red blood cell (Beth-Vincent) and serum (Simonin) tests in ABO blood typing at the Immunology Laboratory of Bouaké University Hospital (Côte d'Ivoire)].Medecine tropicale et sante internationale · 2026Article
- Frequency of Alloimmunization in Patients on Regular Blood Transfusion in Riyadh, Saudi Arabia: A Multicenter Retrospective Study.Journal of clinical medicine · 2026Article
- AlphaGenome-enabled analysis of non-coding regulatory variants underlyingbioRxiv : the preprint server for biology · 2026Article
- Analysis of influencing factors for 5-year transfusion-related adverse events in a tertiary hospital using real-world data.Frontiers in medicine · 2026Article
- Mismatch between global patient blood management policy and nursing education: evidence from four countries.Frontiers in public health · 2026Article
- Knowledge, Attitude, and Practice Regarding Adverse Transfusion Reactions Among Nurses, Physicians, and Transfusion Specialists in China: A Multicenter Cross-Sectional Survey.Journal of multidisciplinary healthcare · 2026Article
- Serological and Clinical Evaluation of Incompatible Crossmatches Encountered in Pre-transfusion Testing.Cureus · 2026Article
- Optimizing Monitoring Frequency During Blood Transfusions: A Review of Guidelines and a Retrospective Cohort to Define a 7-Point Schedule.Nursing reports (Pavia, Italy) · 2025Article
- Improved Clinical and Radiological Outcomes with Double-Cage Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Comparative CT-Based Study.Diagnostics (Basel, Switzerland) · 2025Article
- Blood Transfusions are Associated With Prolonged Mechanical Ventilation Following Cardiac Surgery in Neonates.Reviews in cardiovascular medicine · 2025Article
- Factors Associated With Postoperative Complications Among Critical Patients Undergoing Open-Heart Surgery: A Cross-Sectional Study.Nursing open · 2025Article
- Perioperative Patient Blood Management in Orthopaedics and Traumatology.Malaysian orthopaedic journal · 2025Article
- Effectiveness of training programs on the knowledge of midwifes and nursing responsibilities during blood transfusion at Nasser medical complex, Palestine.Journal of education and health promotion · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blood transfusions have been the cornerstone of life support since the introduction of the ABO classification in the 20th century. The physiologic goal is to restore adequate tissue oxygenation when the demand exceeds the offer. Although it can be a life-saving therapy, blood transfusions can lead to serious adverse effects, and it is essential that physicians remain up to date with the current literature and are aware of the pathophysiology, initial management and risks of each type of transfusion reaction. We aim to provide a structured overview of the pathophysiology, clinical presentation, diagnostic approach and management of acute transfusion reactions based on the literature available in 2022. The numbers of blood transfusions, transfusion reactions and the reporting rate of transfusion reactions differ between countries in Europe. The most frequent transfusion reactions in 2020 were alloimmunizations, febrile non-hemolytic transfusion reactions and allergic transfusion reactions. Transfusion-related acute lung injury, transfusion-associated circulatory overload and septic transfusion reactions were less frequent. Furthermore, the COVID-19 pandemic has challenged the healthcare system with decreasing blood donations and blood supplies, as well as rising concerns within the medical community but also in patients about blood safety and transfusion reactions in COVID-19 patients. The best way to prevent transfusion reactions is to avoid unnecessary blood transfusions and maintain a transfusion-restrictive strategy. Any symptom occurring within 24 h of a blood transfusion should be considered a transfusion reaction and referred to the hemovigilance reporting system. The initial management of blood transfusion reactions requires early identification, immediate interruption of the transfusion, early consultation of the hematologic and ICU departments and fluid resuscitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.