ArticleJournal of clinical medicine2022
Safety of Tacrolimus Monotherapy within 12 Months after Liver Transplantation in the Era of Reduced Tacrolimus and Mycophenolate Mofetil: National Registry Study.
Deok Gie Kim, Sung Hwa Kim, Shin Hwang, Suk Kyun Hong, Je Ho Ryu, Bong-Wan Kim, Young Kyoung You, Donglak Choi, Dong-Sik Kim, Yang Won Nah and 8 more
Open access · goldAbstract read
In one paragraphArticle in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 4 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
18 authors at 11 institutions in 1 country.
Deok Gie KimDepartment of Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.
Sung Hwa KimDepartment of Biostatistics, Yonsei University Wonju College of Medicine, Wonju 26426, Korea.ORCID 0000-0002-5482-1758 Shin HwangDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Suk Kyun HongDepartment of Surgery, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0002-0020-6215 Je Ho RyuDepartment of Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Busan 49241, Korea.
Bong-Wan KimDepartment of Liver Transplantation and Hepatobiliary Surgery, Ajou University School of Medicine, Suwon 16499, Korea.
Young Kyoung YouDepartment of Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Donglak ChoiDepartment of Surgery, Catholic University of Daegu, Daegu 42472, Korea.
Yang Won NahDepartment of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 44033, Korea.ORCID 0000-0001-8161-9849 Jai Young ChoDepartment of Surgery, Seoul National University College of Medicine, Bundang Hospital, Seongnam 13620, Korea.ORCID 0000-0002-1376-956X Tae-Seok KimDepartment of Surgery, Dongsan Medical Center, Keimyung University School of Medicine, Daegu 42601, Korea.
Geun HongDepartment of Surgery, EWHA Womans University College of Medicine, Seoul 07804, Korea.
Dong Jin JooDepartment of Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.
Myoung Soo KimDepartment of Surgery, Yonsei University College of Medicine, Seoul 03722, Korea.
Jong Man KimDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06531, Korea.ORCID 0000-0002-1903-8354 Kotry Study Group
Yonsei University · KRUlsan College · KRAjou University · KRCatholic University of Korea · KRDaegu Catholic University · KREwha Womans University · KRKeimyung University Dongsan Medical Center · KRPusan National University Yangsan Hospital · KRSamsung Medical Center · KRSeoul National University · KRSeoul National University Bundang Hospital · KR
Funding
Korea Disease Control and Prevention Agency 2014-ER6301-00, 2014-ER6301-01, 2014-ER6301-02, 2017-ER6301-00, 2017-ER6301-01, 2017-ER6301-02, 2020-ER7201-00
6 · The paper itselfAbstract
Tacrolimus monotherapy is accepted as a feasible option during early post-liver transplantation as per current international consensus guidelines. However, its effects in the recent era of reduced tacrolimus (TAC) and mycophenolate mofetil (MMF) remain unclear. Liver recipients who either received TAC monotherapy from the treatment onset or switched from TAC/MMF to TAC-mono within 12 months (TAC-mono group; n = 991) were chronologically matched to patients who continued to receive TAC/MMF (TAC/MMF group; n = 991) at the corresponding time points on time-conditional propensity scores. Outcomes within 12 months after matched time points were compared. Biopsy-proven rejection (TAC/MMF: 3.5% vs. TAC-mono: 2.6%;
Indexed as
liver transplantationmycophenolate mofetilrenal dysfunctiontacrolimustime-conditional propensity score
Identifiers
PMID35628939
PMCPMC9145025
OpenAlexW4280615922
What OpenQuestion holds
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LicenceCC BY
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