Evidence map›Paper›PMID 35628855›Full record

ReviewJournal of clinical medicine2022

Mediators of Regional Kidney Perfusion during Surgical Pneumo-Peritoneum Creation and the Risk of Acute Kidney Injury-A Review of Basic Physiology.

Csaba Kopitkó, László Medve, Tibor Gondos, Karim Magdy Mohamed Soliman, Tibor Fülöp

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Improving Patient Outcomes in Abdominal Surgery.Journal of clinical medicine · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Csaba KopitkóDepartment of Anesthesiology and Intensive Therapy, Uzsoki Teaching Hospital, Semmelweis University, H-1145 Budapest, Hungary.ORCID 0000-0002-1922-7294
László MedveDepartment of Anesthesiology and Intensive Therapy, Markhot Ferenc Teaching Hospital, H-3300 Eger, Hungary.
Tibor GondosDoctoral School of Pathological Sciences, Semmelweis University, H-1088 Budapest, Hungary.ORCID 0000-0003-0282-0785
Karim Magdy Mohamed SolimanDepartment of Medicine, Division of Nephrology, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-0960-2644
Tibor FülöpDepartment of Medicine, Division of Nephrology, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-3346-7040
Medical University of South Carolina · USSemmelweis University · HUJahn Ferenc Dél-Pesti Kórház és Rendelőintézet · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI), especially if recurring, represents a risk factor for future chronic kidney disease. In intensive care units, increased intra-abdominal pressure is well-recognized as a significant contributor to AKI. However, the importance of transiently increased intra-abdominal pressures procedures is less commonly appreciated during laparoscopic surgery, the use of which has rapidly increased over the last few decades. Unlike the well-known autoregulation of the renal cortical circulation, medulla perfusion is modulated via partially independent regulatory mechanisms and strongly impacted by changes in venous and lymphatic pressures. In our review paper, we will provide a comprehensive overview of this evolving topic, covering a broad range from basic pathophysiology up to and including current clinical relevance and examples. Key regulators of oxidative stress such as ischemia-reperfusion injury, the activation of inflammatory response and humoral changes interacting with procedural pneumo-peritoneum formation and AKI risk will be recounted. Moreover, we present an in-depth review of the interaction of pneumo-peritoneum formation with general anesthetic agents and animal models of congestive heart failure. A better understanding of the relationship between pneumo-peritoneum formation and renal perfusion will support basic and clinical research, leading to improved clinical care and collaboration among specialists.

Indexed as

acute kidney injuryintra-abdominal pressureoxidative stressrenal cortical blood flowrenal lymphatic drainagerenal medullar blood flowvenous congestion

Identifiers

PMID35628855
PMCPMC9142947
OpenAlexW4280604148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.