ArticleJournal of clinical medicine2022
Antibiotic Administration within Two Days after Successful Endoscopic Retrograde Cholangiopancreatography Is Sufficient for Mild and Moderate Acute Cholangitis.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- ShortWorld journal of gastroenterology · 2023Pooled it
- Index-admission versus referred elective endoscopic retrograde cholangiopancreatography (ERCP) for acute cholangitis in a resource-limited referral center: a real-world retrospective cohort study.Surgical endoscopy · 2026Article
- A Comprehensive Review of Digestive Endoscopy-Associated Infections: Bacterial Pathogens, Host Susceptibility, and the Impact of Viral Hepatitis.Microorganisms · 2025Review
- Article
- Navigating antibiotic therapy in acute cholangitis: Best practices and new insights.Journal of hepato-biliary-pancreatic sciences · 2025Review
- Article
- Antimicrobial therapy outcomes in acute cholangitis: Hilar multiple obstructionsJGH open : an open access journal of gastroenterology and hepatology · 2024Article
- Association of short-course antimicrobial therapy and bacterial resistance in acute cholangitis: Retrospective cohort study.Endoscopy international open · 2024Article
- Comparative Analysis of Antibiotic Resistance in Acute Cholangitis Patients with Stent Placement and Sphincterotomy Interventions.Life (Basel, Switzerland) · 2023Article
- Clinical Advances in the Diagnosis and Treatment of Biliary Tract Diseases.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To prevent the increase of resistant bacteria, it is important to minimize the use of antimicrobial agents. Studies have found that administration for ≤3 days after successful endoscopic retrograde cholangiopancreatography (ERCP) is appropriate. Therefore, the present study aimed to verify if administration of antimicrobial agents can be further shortened to ≤2 days after ERCP. We divided 390 patients with mild and moderate cholangitis who underwent technically successful ERCP from January 2018 to June 2020 and had positive blood or bile cultures into two groups: antibiotic therapy within two days of ERCP (short-course therapy, SCT; n = 59, 15.1%), and for >3 days (long-course therapy, LCT; n = 331, 84.9%). The increased severity after admission and other outcomes were compared between the two groups, and the risk factors for increased severity were verified. There were no between-group differences in patient characteristics. Total length of hospital stay was shorter in SCT than in LCT, and other outcomes in SCT were not significantly different from those in LCT. Being 80 or older was a risk factor for increased severity; however, SCT was not associated with increased severity. Antimicrobial therapy for ≤2 days after successful ERCP is adequate in patients with mild and moderate acute cholangitis.
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Registered trials
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