Evidence map›Paper›PMID 35628769›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

The

Daniel Yuri Akiyama, Marina Campos Rocha, Jonas Henrique Costa, Caroline Brandão Teles, Giuliana da Silva Zuccoli, Iran Malavazi, Taicia Pacheco Fill

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
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  5. Article
  6. Review
  7. Regulation of Secondary Metabolism in theInternational journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daniel Yuri AkiyamaDepartment of Organic Chemistry, Institute of Chemistry, State University of Campinas, Campinas 13083-970, SP, Brazil.ORCID 0000-0003-2859-1992
Marina Campos RochaDepartment of Genetic and Evolution, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.
Jonas Henrique CostaDepartment of Organic Chemistry, Institute of Chemistry, State University of Campinas, Campinas 13083-970, SP, Brazil.ORCID 0000-0002-6415-3984
Caroline Brandão TelesDepartment of Biochemistry and Tissue Biology, Institute of Biology, State University of Campinas, Campinas 13083-970, SP, Brazil.
Giuliana da Silva ZuccoliDepartment of Biochemistry and Tissue Biology, Institute of Biology, State University of Campinas, Campinas 13083-970, SP, Brazil.
Iran MalavaziDepartment of Genetic and Evolution, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0000-0002-4526-4961
Taicia Pacheco FillDepartment of Organic Chemistry, Institute of Chemistry, State University of Campinas, Campinas 13083-970, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de São Carlos · BR

Funding

São Paulo Research Foundation 2016/07870-9, 2017/19694-3, 2017/25055-3, 2018/00315-5, 2018/13027-8, 2018/14666-4, 2019/06359-7
6 · The paper itself

Abstract

Most of the biosynthetic gene clusters (BGCs) found in microbes are silent under standard laboratory cultivation conditions due to the lack of expression triggering stimuli, representing a considerable drawback in drug discovery. To access the full biosynthetic potential, studies towards the activation of cryptic BGCs are essential. Histone acetylation status is an important regulator of chromatin structure, which impacts cell physiology and the expression of BGCs. In this study,

Indexed as

epigenetic modulationnatural product biosynthesis regulationreactive oxygen species

Identifiers

PMID35628769
PMCPMC9146837
OpenAlexW4280611159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.