Evidence map›Paper›PMID 35628743›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Is ß-d-glucan Relevant for the Diagnosis and Follow-Up of Intensive Care Patients with Yeast-Complicated Intra-Abdominal Infection?

Hervé Dupont, Stéphanie Malaquin, Léonie Villeret, Pierre-Yves Macq, Nacim Ammenouche, François Tinturier, Momar Diouf, Matthieu Rumbach, Taieb Chouaki

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03140748 (Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03140748 nacompletednot on this map

Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation

TypeinterventionalSponsorCentre Hospitalier Universitaire, AmiensRan2018 to 2023Enrolled70ConditionsPeritonitis Infectious, Candida InfectionArmsTo evaluate the initial levels and kinetics of serum β-D-glucan
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review on the management of intra-abdominal candidiasis.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hervé DupontSurgical ICU, Department of Anesthesiology and Critical Care Medicine, University Hospital of Amiens Picardy, 80054 Amiens, France.ORCID 0000-0002-5644-3412
Stéphanie MalaquinSurgical ICU, Department of Anesthesiology and Critical Care Medicine, University Hospital of Amiens Picardy, 80054 Amiens, France.
Léonie VilleretSurgical ICU, Department of Anesthesiology and Critical Care Medicine, University Hospital of Amiens Picardy, 80054 Amiens, France.
Pierre-Yves MacqSurgical ICU, Department of Anesthesiology and Critical Care Medicine, University Hospital of Amiens Picardy, 80054 Amiens, France.
Nacim AmmenoucheSurgical ICU, Department of Anesthesiology and Critical Care Medicine, University Hospital of Amiens Picardy, 80054 Amiens, France.
François TinturierSurgical ICU, Department of Anesthesiology and Critical Care Medicine, University Hospital of Amiens Picardy, 80054 Amiens, France.
Momar DioufBiostatistical Unit, Direction de la Recherche Clinique, University Hospital of Amiens Picardy, 80054 Amiens, France.
Matthieu RumbachSurgical ICU, Department of Anesthesiology and Critical Care Medicine, University Hospital of Amiens Picardy, 80054 Amiens, France.ORCID 0000-0003-4836-5570
Taieb ChouakiMycology Laboratory, University Hospital of Amiens Picardy, 80054 Amiens, France.
Centre Hospitalier Universitaire Amiens-Picardie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The usefulness of (1,3)-ß-d-glucan (BDG) detection for the diagnosis of intra-abdominal candidiasis and treatment monitoring is unknown. A prospective, single-center study of consecutive patients admitted to an ICU with complicated intra-abdominal infection (IAI) over a 2-year period was conducted. BDG was measured in the peritoneal fluid and serum between day 1 (D1) and D10. Patients with a positive peritoneal fluid yeast culture (YP) were compared to those with a negative yeast culture (YN). The evolution of serum BDG was compared in the two groups. Seventy patients were included (sixty-five analyzed): YP group (n = 19) and YN group (n = 46). Median peritoneal BDG concentration during surgery was 2890 pg.mL

Indexed as

candidiasisintensive care unitintra-abdominal infection">d-glucanß-

Identifiers

PMID35628743
PMCPMC9143807
OpenAlexW4229061151

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.