Evidence map›Paper›PMID 35628612›Full record

ReviewInternational journal of molecular sciences2022

Histone Modifications and Non-Coding RNAs: Mutual Epigenetic Regulation and Role in Pathogenesis.

Irina V Bure, Marina V Nemtsova, Ekaterina B Kuznetsova

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  3. The Role of Hydrogen Sulfide (HInternational journal of molecular sciences · 2023
    Pooled it
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Irina V BureLaboratory of Medical Genetics, I. M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Marina V NemtsovaLaboratory of Medical Genetics, I. M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Ekaterina B KuznetsovaLaboratory of Medical Genetics, I. M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.

Funding

Russian Science Foundation 20-75-10117
6 · The paper itself

Abstract

In the last few years, more and more scientists have suggested and confirmed that epigenetic regulators are tightly connected and form a comprehensive network of regulatory pathways and feedback loops. This is particularly interesting for a better understanding of processes that occur in the development and progression of various diseases. Appearing on the preclinical stages of diseases, epigenetic aberrations may be prominent biomarkers. Being dynamic and reversible, epigenetic modifications could become targets for a novel option for therapy. Therefore, in this review, we are focusing on histone modifications and ncRNAs, their mutual regulation, role in cellular processes and potential clinical application.

Indexed as

Epigenesis, GeneticHistone CodeDNA MethylationProtein Processing, Post-TranslationalRNA, UntranslatedRNA, Untranslatedbiomarkerepigeneticshistone modificationsnon-coding RNAs

Identifiers

PMID35628612
PMCPMC9146199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.