Evidence map›Paper›PMID 35628609›Full record

ArticleInternational journal of molecular sciences2022

Altered Blood and Brain Expression of Inflammation and Redox Genes in Alzheimer's Disease, Common to APP

Catalina Anca Cucos, Elena Milanesi, Maria Dobre, Ioana Andreea Musat, Gina Manda, Antonio Cuadrado

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Inflammatory protein associations with brain MRI measures: Framingham Offspring Cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Catalina Anca CucosVictor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Elena MilanesiVictor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Maria DobreVictor Babes National Institute of Pathology, 050096 Bucharest, Romania.
Ioana Andreea MusatFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Gina MandaVictor Babes National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-9706-1883
Antonio CuadradoVictor Babes National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-4039-7140
Institutul National Victor Babes · ROBiomedical Research Networking Center on Neurodegenerative Diseases · ESCarol Davila University of Medicine and Pharmacy · RO

Funding

Competitiveness Operational Programme 2014-2020 P37_732Romanian Ministry of Research, Innovation and Digitization 31PFE/30.12.2021
6 · The paper itself

Abstract

Despite intensive research, the pathophysiology of Alzheimer's disease (AD) is still not fully understood, and currently there are no effective treatments. Therefore, there is an unmet need for reliable biomarkers and animal models of AD to develop innovative therapeutic strategies addressing early pathologic events such as neuroinflammation and redox disturbances. The study aims to identify inflammatory and redox dysregulations in the context of AD-specific neuronal cell death and DNA damage, using the APP

Indexed as

Alzheimer DiseaseAmyloid beta-Protein PrecursorAnimalsBrainHumansInflammationMiceMice, TransgenicOxidation-ReductionAmyloid beta-Protein PrecursorAlzheimer’s diseasebloodgene expressionhippocampusinflammationredox alterations

Identifiers

PMID35628609
PMCPMC9144576
OpenAlexW4281250589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.