Evidence map›Paper›PMID 35628596›Full record

ArticleInternational journal of molecular sciences2022

Different Effects of RNAi-Mediated Downregulation or Chemical Inhibition of NAMPT in an Isogenic IDH Mutant and Wild-Type Glioma Cell Model.

Maximilian Clausing, Doreen William, Matthias Preussler, Julia Biedermann, Konrad Grützmann, Susan Richter, Frank Buchholz, Achim Temme, Evelin Schröck, Barbara Klink

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maximilian ClausingInstitute for Clinical Genetics, University Hospital Carl Gustav Carus, Technische Universität Dresden, ERN-GENTURIS, Hereditary Cancer Syndrome Center Dresden, 01307 Dresden, Germany.
Doreen WilliamInstitute for Clinical Genetics, University Hospital Carl Gustav Carus, Technische Universität Dresden, ERN-GENTURIS, Hereditary Cancer Syndrome Center Dresden, 01307 Dresden, Germany.ORCID 0000-0001-7824-5073
Matthias PreusslerInstitute for Clinical Genetics, University Hospital Carl Gustav Carus, Technische Universität Dresden, ERN-GENTURIS, Hereditary Cancer Syndrome Center Dresden, 01307 Dresden, Germany.
Julia BiedermannInstitute for Clinical Genetics, University Hospital Carl Gustav Carus, Technische Universität Dresden, ERN-GENTURIS, Hereditary Cancer Syndrome Center Dresden, 01307 Dresden, Germany.
Konrad GrützmannGerman Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0001-8942-0287
Susan RichterInstitute for Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0002-3549-2477
Frank BuchholzNational Center for Tumor Diseases Partner Site Dresden (NCT/UCC), German Cancer Consortium (DKTK), 01307 Dresden, Germany.ORCID 0000-0002-4577-3344
Achim TemmeNational Center for Tumor Diseases Partner Site Dresden (NCT/UCC), German Cancer Consortium (DKTK), 01307 Dresden, Germany.ORCID 0000-0001-5084-1180
Evelin SchröckInstitute for Clinical Genetics, University Hospital Carl Gustav Carus, Technische Universität Dresden, ERN-GENTURIS, Hereditary Cancer Syndrome Center Dresden, 01307 Dresden, Germany.
Barbara KlinkInstitute for Clinical Genetics, University Hospital Carl Gustav Carus, Technische Universität Dresden, ERN-GENTURIS, Hereditary Cancer Syndrome Center Dresden, 01307 Dresden, Germany.ORCID 0000-0002-8753-8238
German Cancer Research Center · DEUniversity Hospital Carl Gustav Carus · DENational Center for Tumor Diseases · DE

Funding

Else Kröner-Fresenius-Stiftung Else Kröner-Promotionskolleg Dresden (M.C.)German Cancer Aid #70112014
6 · The paper itself

Abstract

The IDH1

Indexed as

Brain NeoplasmsCytokinesGlioblastomaGliomaIsocitrate DehydrogenaseNicotinamide PhosphoribosyltransferaseDown-RegulationHumansNADNADPRNA InterferenceCytokinesIDH1 protein, humanIsocitrate DehydrogenaseNADNADPNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humangliomaIDH1 mutationNAD+ synthesisnicotinamide phosphoribosyltransferaseredox household

Identifiers

PMID35628596
PMCPMC9143996
OpenAlexW4281255784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.