Evidence map›Paper›PMID 35628578›Full record

ArticleInternational journal of molecular sciences2022

Association of DNA Methylation of the

Kyu-Man Han, Kwan Woo Choi, Aram Kim, Wooyoung Kang, Youbin Kang, Woo-Suk Tae, Mi-Ryung Han, Byung-Joo Ham

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Brain fog in central disorders of hypersomnolence: a review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Review
  11. New Insights on NLRP3 Inflammasome: Mechanisms of Activation, Inhibition, and Epigenetic Regulation.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kyu-Man HanDepartment of Psychiatry, Korea University Anam Hospital, Korea University College of Medicine, Seoul 02841, Korea.
Kwan Woo ChoiDepartment of Psychiatry, Korea University Anam Hospital, Korea University College of Medicine, Seoul 02841, Korea.
Aram KimDepartment of Biomedical Sciences, Korea University College of Medicine, Seoul 02841, Korea.
Wooyoung KangDepartment of Biomedical Sciences, Korea University College of Medicine, Seoul 02841, Korea.
Youbin KangDepartment of Biomedical Sciences, Korea University College of Medicine, Seoul 02841, Korea.
Woo-Suk TaeBrain Convergence Research Center, Korea University College of Medicine, Seoul 02841, Korea.
Mi-Ryung HanDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon 22012, Korea.
Byung-Joo HamDepartment of Psychiatry, Korea University Anam Hospital, Korea University College of Medicine, Seoul 02841, Korea.ORCID 0000-0002-0108-2058
Korea University · KRKorea University Medical Center · KRIncheon National University · KR

Funding

National Research Foundation of Korea NRF-2020M3E5D9080792National Research Foundation of Korea NRF-2020R1C1C1012288National Research Foundation of Korea NRF- 2022R1A2C4001313
6 · The paper itself

Abstract

The Nod-like receptor pyrin containing 3 (NLRP3) inflammasome has been reported to be a convergent point linking the peripheral immune response induced by psychological stress and neuroinflammatory processes in the brain. We aimed to identify differences in the methylation profiles of the

Indexed as

Cerebral CortexDNA MethylationMajor Depressive DisorderNLR Family, Pyrin Domain-Containing 3 ProteinBrainHumansInflammasomesMagnetic Resonance ImagingInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humancortical thicknessdepressionDNA methylationepigeneticsmagnetic resonance imagemajor depressive disorderneuroimagingneuroinflammationNLRP3

Identifiers

PMID35628578
PMCPMC9143533
OpenAlexW4281256773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.