Evidence map›Paper›PMID 35628499›Full record

ArticleInternational journal of molecular sciences2022

Correlation of Immunological and Molecular Profiles with Response to Crizotinib in Alveolar Soft Part Sarcoma: An Exploratory Study Related to the EORTC 90101 "CREATE" Trial.

Che-Jui Lee, Elodie Modave, Bram Boeckx, Bernd Kasper, Steinar Aamdal, Michael G Leahy, Piotr Rutkowski, Sebastian Bauer, Maria Debiec-Rychter, Raf Sciot and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 5 countries.

Che-Jui LeeLaboratory of Experimental Oncology, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-9078-5929
Elodie ModaveVIB Center for Cancer Biology, VIB and Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium.
Bram BoeckxVIB Center for Cancer Biology, VIB and Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium.
Bernd KasperSarcoma Unit, Interdisciplinary Tumor Center, Mannheim University Medical Center, 68167 Mannheim, Germany.
Steinar AamdalDepartment of Oncology, Oslo University Hospital, 0315 Oslo, Norway.
Michael G LeahyThe Christie NHS Foundation Trust, Manchester M20 4BX, UK.
Piotr RutkowskiDepartment of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, 00-001 Warsaw, Poland.ORCID 0000-0002-8920-5429
Sebastian BauerGerman Cancer Consortium (DKTK), Partner Site University Hospital Essen, 45147 Essen, Germany.
Maria Debiec-RychterDepartment of Human Genetics, University Hospitals Leuven, KU Leuven, 3000 Leuven, Belgium.
Raf SciotDepartment of Pathology, University Hospitals Leuven, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-2244-5839
Diether LambrechtsVIB Center for Cancer Biology, VIB and Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium.
Agnieszka WozniakLaboratory of Experimental Oncology, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-9726-144X
Patrick SchöffskiLaboratory of Experimental Oncology, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-5980-030X
KU Leuven · BEVIB-KU Leuven Center for Cancer Biology · BEEssen University Hospital · DEHeidelberg University · DEOslo University Hospital · NOThe Christie NHS Foundation Trust · GBThe Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

Stichting tegen Kanker n/aTaiwanese Ministry of Education n/a
6 · The paper itself

Abstract

Alveolar soft part sarcoma (ASPS) is a rare subtype of soft tissue sarcoma characterized by an unbalanced translocation, resulting in ASPSCR1-TFE3 fusion that transcriptionally upregulates

Indexed as

Sarcoma, Alveolar Soft PartSoft Tissue NeoplasmsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCrizotinibHumansTranslocation, GeneticTumor MicroenvironmentBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCrizotinibalveolar soft part sarcomaCREATEcrizotinibgene alterationimmunological characterizationmolecular profilingtumor microenvironment

Identifiers

PMID35628499
PMCPMC9145625
OpenAlexW4280612056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.