The DEAD-Box Protein Rok1 Coordinates Ribosomal RNA Processing in Association with Rrp5 in

Jie Chen, Yuantai Huang, Kang Zhang

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 49% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Exploring the Possibility of RNA in Diverse Biological Processes.International journal of molecular sciences · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jie ChenGuangdong Provincial Key Laboratory of High Technology for Plant Protection, Plant Protection Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.ORCID 0000-0002-7029-6674

Yuantai HuangState Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.

Kang ZhangState Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.

Sun Yat-sen University · CN

Funding

Guangdong Academy of Sciences of Talent Introduction R2021YJ-QG002

6 · The paper itself

Abstract

Ribosome biogenesis and processing involve the coordinated action of many components. The DEAD-box RNA helicase (Rok1) is essential for cell viability, and the depletion of Rok1 inhibits pre-rRNA processing. Previous research on Rok1 and its cofactor Rrp5 has been performed primarily in yeast. Few functional studies have been performed in complex multicellular eukaryotes. Here, we used a combination of genetics and developmental experiments to show that Rok1 and Rrp5, which localize to the nucleolus, play key roles in the pre-rRNA processing and ribosome assembly in

Indexed as

DEAD-box RNA HelicasesDrosophila melanogasterNuclear ProteinsRNA-Binding ProteinsAnimalsDrosophila ProteinsIn Situ Hybridization, FluorescenceRibosomesRNA PrecursorsRNA Processing, Post-TranscriptionalRNA, Ribosomalais protein, DrosophilaDEAD-box RNA HelicasesDrosophila ProteinsNuclear ProteinsRNA-Binding ProteinsRNA PrecursorsRNA, Ribosomalpre-rRNARBPsribosomal RNARok1Rrp5

Identifiers

PMID35628496

DOI10.3390/ijms23105685

PMCPMC9146779

OpenAlexW4280556596

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.