Evidence map›Paper›PMID 35628478›Full record

ReviewInternational journal of molecular sciences2022

Penicillin-Binding Proteins, β-Lactamases, and β-Lactamase Inhibitors in β-Lactam-Producing Actinobacteria: Self-Resistance Mechanisms.

Juan F Martin, Ruben Alvarez-Alvarez, Paloma Liras

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  7. Review
  8. Why Do FilamentousAnnual review of microbiology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Facile Synthesis of 5-Bromo-Infection and drug resistance · 2024
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Juan F MartinDepartamento de Biología Molecular, Universidad de León, 24071 León, Spain.
Ruben Alvarez-AlvarezDepartamento de Biología Molecular, Universidad de León, 24071 León, Spain.
Paloma LirasDepartamento de Biología Molecular, Universidad de León, 24071 León, Spain.
Universidad de León · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human society faces a serious problem due to the widespread resistance to antibiotics in clinical practice. Most antibiotic biosynthesis gene clusters in actinobacteria contain genes for intrinsic self-resistance to the produced antibiotics, and it has been proposed that the antibiotic resistance genes in pathogenic bacteria originated in antibiotic-producing microorganisms. The model actinobacteria

Indexed as

Actinobacteriabeta-Lactamase Inhibitorsbeta-LactamasesPenicillin-Binding ProteinsAnti-Bacterial Agentsbeta-LactamsCephalosporinsCephamycinsClavulanic AcidPenicillinsAnti-Bacterial Agentsbeta-Lactamase Inhibitorsbeta-Lactamasesbeta-LactamsCephalosporinsCephamycinsClavulanic AcidPenicillin-Binding ProteinsPenicillinsantibiotic resistancecephamycin Cclavulanic acidclusters organization and evolutionpenicillin-binding proteinsStreptomyces clavuligerussuperclustersβ-lactamases

Identifiers

PMID35628478
PMCPMC9146315
OpenAlexW4280554372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.