Evidence map›Paper›PMID 35628418›Full record

ArticleInternational journal of molecular sciences2022

Brain Proteome and Behavioural Analysis in Wild Type, BDNF

Elisa Maffioli, Elisa Angiulli, Simona Nonnis, Francesca Grassi Scalvini, Armando Negri, Gabriella Tedeschi, Ivan Arisi, Flavia Frabetti, Salvatore D'Aniello, Enrico Alleva and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Elisa MaffioliDepartment of Veterinary Medicine and Animal Science, Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-5539-1825
Elisa AngiulliDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Via Alfonso Borelli 50, 00161 Rome, Italy.
Simona NonnisDepartment of Veterinary Medicine and Animal Science, Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-3453-7282
Francesca Grassi ScalviniDepartment of Veterinary Medicine and Animal Science, Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Armando NegriDepartment of Veterinary Medicine and Animal Science, Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Gabriella TedeschiDepartment of Veterinary Medicine and Animal Science, Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Ivan ArisiBioinformatics Facility, European Brain Research Institute (EBRI) "Rita Levi-Montalcini", 00161 Rome, Italy.
Flavia FrabettiDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, 40136 Bologna, Italy.
Salvatore D'AnielloBiology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn Napoli, Villa Comunale, 80121 Napoli, Italy.ORCID 0000-0001-7294-1465
Enrico AllevaCenter for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Carla CioniDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Via Alfonso Borelli 50, 00161 Rome, Italy.
Mattia ToniDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, Via Alfonso Borelli 50, 00161 Rome, Italy.ORCID 0000-0001-7167-4051
University of Milan · ITSapienza University of Rome · ITIstituto di Farmacologia Traslazionale · ITIstituto Superiore di Sanità · ITStazione Zoologica Anton Dohrn · ITUniversity of Bologna · IT

Funding

FIRB (Futuro in Ricerca 2012) RBFR12QW4I_002Sapienza University of Rome (Progetti di Ricerca 2016) RM116154BDC475ADSapienza University of Rome (Progetti di Ricerca 2019) RM11916B645E99AFSapienza University of Rome (Progetti di Ricerca 2021) RM12117A383FC177
6 · The paper itself

Abstract

Experimental evidence suggests that environmental stress conditions can alter the expression of BDNF and that the expression of this neurotrophin influences behavioural responses in mammalian models. It has been recently demonstrated that exposure to 34 °C for 21 days alters the brain proteome and behaviour in zebrafish. The aim of this work was to investigate the role of BDNF in the nervous system of adult zebrafish under control and heat treatment conditions. For this purpose, zebrafish from three different genotypes (wild type, heterozygous BDNF

Indexed as

ProteomeZebrafishAnimalsBehavior Rating ScaleBrainBrain-Derived Neurotrophic FactorMammalsProteomicsTemperatureBrain-Derived Neurotrophic FactorProteomeBDNFbehaviourproteomictemperaturezebrafish

Identifiers

PMID35628418
PMCPMC9146406
OpenAlexW4280597580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.